基于自组装荧光纳米颗粒的光可调多色荧光成像
Photo-tunable multicolour fluorescence imaging based on self-assembled fluorogenic nanoparticles.
作者信息
Montalti Marco, Battistelli Giulia, Cantelli Andrea, Genovese Damiano
机构信息
Department of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, I-40126, Bologna, Italy.
出版信息
Chem Commun (Camb). 2014 May 25;50(40):5326-9. doi: 10.1039/c3cc48464e. Epub 2014 Jan 10.
PMID:24406426
Abstract
Non-fluorescent nanoparticles resulting from the self-assembly of a new perylene diimide behave as fluorogenic probes for biological cells under physiological conditions giving a dosage-dependent green or red fluorescence and showing very low cytotoxicity. The emission colour can be tuned by photo-irradiation to achieve multicolour labelling.
摘要
一种新型苝二酰亚胺自组装形成的非荧光纳米颗粒，在生理条件下可作为生物细胞的荧光探针，发出剂量依赖性的绿色或红色荧光，且细胞毒性极低。发射颜色可通过光照射进行调节，以实现多色标记。
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