Pescosolido Nicola, Stefanucci Alessio, Buomprisco Giuseppe, Fazio Stefano
J Pediatr Ophthalmol Strabismus. 2014 Mar-Apr;51(2):78-86. doi: 10.3928/01913913-20130107-01. Epub 2014 Jan 14.
Amblyopia is a unilateral or bilateral reduction of visual acuity secondary to abnormal visual experience during early childhood. It is one of the most common causes of vision loss and monocular blindness and is commonly associated with strabismus, anisometropia, and visual deprivation (in particular congenital cataract and ptosis). It is clinically defined as a two-line difference of best-corrected visual acuity between the eyes. The purpose of this study was to understand the neural mechanisms of amblyopia and summarize the current therapeutic strategies. In particular, the authors focused on the concept of brain plasticity and its implication for new treatment strategies for children and adults with amblyopia.
弱视是一种继发于幼儿期异常视觉经历的单眼或双眼视力下降。它是视力丧失和单眼失明的最常见原因之一，通常与斜视、屈光参差和视觉剥夺（特别是先天性白内障和上睑下垂）有关。临床上将其定义为双眼最佳矫正视力相差两行。本研究的目的是了解弱视的神经机制并总结当前的治疗策略。特别是，作者重点关注了脑可塑性的概念及其对弱视儿童和成人新治疗策略的意义。
