Xu C, Wise F W
School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853.
Nat Photonics. 2013 Nov 1;7. doi: 10.1038/nphoton.2013.284.
Nonlinear microscopy techniques developed over the past two decades have provided dramatic new capabilities for biological imaging. The initial demonstrations of nonlinear microscopies coincided with the development of solid-state femtosecond lasers, which continue to dominate applications of nonlinear microscopy. Fiber lasers offer attractive features for biological and biomedical imaging, and recent advances are leading to high-performance sources with the potential for robust, inexpensive, integrated instruments. This article discusses recent advances, and identifies challenges and opportunities for fiber lasers in nonlinear bioimaging.
在过去二十年中发展起来的非线性显微镜技术为生物成像提供了全新的强大功能。非线性显微镜的最初演示与固态飞秒激光器的发展同步,固态飞秒激光器至今仍在非线性显微镜应用中占据主导地位。光纤激光器为生物和生物医学成像提供了有吸引力的特性,最近的进展正促使产生高性能光源,有望用于坚固、廉价的集成仪器。本文讨论了最近的进展,并确定了光纤激光器在非线性生物成像中的挑战和机遇。