Wohlrab J
Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle (Saale), Deutschland,
Hautarzt. 2014 Mar;65(3):169-74. doi: 10.1007/s00105-013-2654-6.
Numerous dermatoses are treated with topically applied substances. Planning, conception, implementation and monitoring of topical therapies are dermatological core competencies. This requires fundamental knowledge about the physicochemical structure of skin layers, especially the stratum corneum, as well as about the interaction of both the active substance and the vehicle system with the skin. Professional treatment also requires basic knowledge about pharmacokinetics and the special features of epicutaneous drug administration.
许多皮肤病都采用局部应用药物进行治疗。局部治疗的规划、构思、实施和监测是皮肤科的核心能力。这需要掌握有关皮肤各层，尤其是角质层的物理化学结构，以及活性物质和载体系统与皮肤相互作用的基础知识。专业治疗还需要了解药代动力学以及经皮给药的特殊特点等基础知识。
