Cheok Stephanie, Chen Jason, Lazareff Jorge
Department of Neurosurgery, UCLA David Geffen School of Medicine, 10833 Le Conte Avenue, 13-154 CHS, Los Angeles, CA, 90095, USA.
Childs Nerv Syst. 2014 Apr;30(4):599-606. doi: 10.1007/s00381-013-2327-x. Epub 2014 Jan 15.
Overdrainage, siphoning, and slit-ventricle syndrome are well-documented complications of shunting in hydrocephalic patients. Despite the prevalence of these conditions, their mechanisms are still not fully understood. In this paper, the authors trace the concept of overdrainage and the related phenomena of siphoning and slit-ventricle syndrome.
To provide a historical overview of overdrainage and to reignite discussion of a topic that has been settled.
A medical literature search and review were performed via Google Scholar. Of 565 publications, 3 primary papers were identified and a timeline was developed demonstrating the convergence of the aforementioned concepts. From the primary papers, 25 relevant publications were selected and further analyzed searching for hypothesis, evidence, and conclusions.
Overdrainage, siphoning, and slit-ventricle syndrome are associated concepts that have converged into a pathophysiological theory where siphoning of CSF leads to overdrainage, which is then hypothesized to cause slit-ventricle syndrome in a small subset of patients. Our data suggests that while there have been numerous reports regarding overdrainage and its consequences, the evidence is not as robust as currently presumed and this subject requires prospective exploration.
脑脊液过度引流、虹吸现象和裂隙脑室综合征是脑积水患者分流术后有充分文献记载的并发症。尽管这些情况很常见，但其机制仍未完全明确。在本文中，作者追溯了脑脊液过度引流的概念以及相关的虹吸现象和裂隙脑室综合征。
提供脑脊液过度引流的历史概述，并重新引发对一个已定论话题的讨论。
通过谷歌学术进行医学文献检索和综述。在565篇出版物中，确定了3篇主要论文，并绘制了一条时间线，展示上述概念的融合情况。从主要论文中，挑选出25篇相关出版物并进一步分析，以寻找假设、证据和结论。
脑脊液过度引流、虹吸现象和裂隙脑室综合征是相关概念，已融合为一种病理生理理论，即脑脊液的虹吸作用导致过度引流，进而推测在一小部分患者中会引发裂隙脑室综合征。我们的数据表明，虽然有大量关于脑脊液过度引流及其后果的报道，但证据并不像目前认为的那样确凿，这个问题需要前瞻性探索。
