Dhar Arun K, Manna Sanjib K, Thomas Allnutt F C
BrioBiotech Corp, P.O. Box 26, Glenelg, MD 21737 USA.
Central Inland Fisheries Research Institute, Barrackpore, West Bengal India.
Virusdisease. 2014 Jan;25(1):1-17. doi: 10.1007/s13337-013-0186-4. Epub 2013 Dec 3.
Over the past decade, aquaculture has grown at an average annual growth rate of approximately 6 % worldwide despite many challenges. Viral diseases are one of the major challenges that are threatening a sustainable growth of finfish farming globally. Vaccination of farmed fish plays an important role in commercial fish farming to mitigate viral diseases. In this review, we summarized the major viral diseases that have caused serious economic losses, and emerging diseases that pose a potential threat to aquaculture. The current status of viral vaccines in farmed fish are discussed, particularly the different types of vaccines that were licensed in recent years and are now commercially available, and the routes of delivery of those vaccines including the merits and demerits of each of these delivery method. Furthermore, the article provides an overview of different experimental vaccines that have been reported in the literatures in recent years besides highlighting the future need for developing cost-effective, oral vaccines that can be easily applicable at farm level.
在过去十年中,尽管面临诸多挑战,但全球水产养殖的年平均增长率约为6%。病毒性疾病是威胁全球养殖鱼类可持续发展的主要挑战之一。养殖鱼类的疫苗接种在商业养鱼业中对减轻病毒性疾病起着重要作用。在本综述中,我们总结了造成严重经济损失的主要病毒性疾病以及对水产养殖构成潜在威胁的新出现疾病。讨论了养殖鱼类病毒性疫苗的现状,特别是近年来获得许可并已上市的不同类型疫苗,以及这些疫苗的接种途径,包括每种接种方法的优缺点。此外,本文概述了近年来文献中报道的不同实验性疫苗,同时强调了未来开发具有成本效益、易于在养殖场应用的口服疫苗的必要性。