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老年人的微创食管切除术

Minimally invasive esophagectomy in the elderly.

作者信息

Puntambekar Shailesh, Kenawadekar Rahul, Pandit Archit, Nadkarni Akshay, Joshi Saurabh, Agarwal Geetanjali, Bhat Nasir Ahmad, Malik Jainul, Reddy Sunil

机构信息

Department of Minimal Access Surgery, Galaxy Care Laparoscopic Institute, Karve Road, Pune, India.

出版信息

Indian J Surg Oncol. 2013 Dec;4(4):326-31. doi: 10.1007/s13193-013-0263-6. Epub 2013 Aug 24.

DOI:10.1007/s13193-013-0263-6
PMID:24426751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3890021/
Abstract

OBJECTIVE

A retrospective analysis of a prospectively maintained database to evaluate our experience in elderly patients (>70 years) undergoing Thoracolaparoscopic esophagectomy for cancer oesophagus. To ascertain whether age, is a limiting factor for patients undergoing minimally invasive esophagectomy.

METHODS

All Patients above 70 years of age, referred to the Gastro-esophageal clinic were included in the study. Tumours were staged as per AJCC 6th ed. 2002. Patients diagnosed with T1/2/3, N0/1 lesion of the mid/lower oesophagus (Infra Azygous) and type I and II Gastro esophageal junction tumours were included in the study. Patients with ASA grade IV were excluded. All patients who underwent Thoracolaparoscopic esophagectomy from January 2009 till January 2012 were evaluated for their perioperative outcomes.

RESULTS

Sixty eight patients underwent Minimal Invasive esophagectomy from January 2009 to January 2012. There were 45 males and 23 females. The average age in elderly group was 75.76 ± 5.96 years (range 70 to 91). Mean operative time was 178.84 ± 65.26 min, mean blood loss 143.84 ml(range 32-450 ml), mean ICU stay 3.84 days(range 2-11 days) and mean hospital stay was 12.76 days(range 8-21 days). Pneumonia and Cardiac related complications occurred in 10.30 % and 1.47 % patients respectively. None of the procedures required conversion to open thoracotomy.

CONCLUSIONS

Thoracolaparoscopic esophagectomy is feasible and surgically safe in elderly patients with low morbidity and mortality. Thus age of a patient should not be considered a limiting factor.

ULTRAMINI ABSTRACT

This is an original article about our experience of thoracolaparoscopic esophagectomy for cancer esophagus in elderly patients. After analyzing the data we feel that age of the patient cannot be a truly limiting factor for patient diagnosed of esophageal cancer to undergo minimally invasive esophagectomy.

摘要

目的

对一个前瞻性维护的数据库进行回顾性分析,以评估我们在老年患者(>70岁)中进行胸腹腔镜联合食管癌切除术的经验。确定年龄是否是接受微创食管癌切除术患者的限制因素。

方法

纳入所有转诊至胃食管诊所的70岁以上患者。肿瘤根据2002年美国癌症联合委员会(AJCC)第6版进行分期。研究纳入诊断为中/下段食管(奇静脉以下)T1/2/3、N0/1病变以及I型和II型胃食管交界肿瘤的患者。排除美国麻醉医师协会(ASA)分级为IV级的患者。对2009年1月至2012年1月期间所有接受胸腹腔镜联合食管癌切除术的患者的围手术期结果进行评估。

结果

2009年1月至2012年1月期间,68例患者接受了微创食管癌切除术。其中男性45例,女性23例。老年组的平均年龄为75.76±5.96岁(范围70至91岁)。平均手术时间为178.84±65.26分钟,平均失血量为143.84毫升(范围32 - 450毫升);平均重症监护病房(ICU)停留时间为3.84天(范围2 - 11天),平均住院时间为12.76天(范围8 - 21天)。肺炎和心脏相关并发症分别发生在10.30%和1.47%的患者中。所有手术均无需转为开胸手术。

结论

胸腹腔镜联合食管癌切除术在老年患者中是可行的,手术安全性高,发病率和死亡率低。因此,患者年龄不应被视为限制因素。

超短摘要

这是一篇关于我们在老年患者中进行胸腹腔镜联合食管癌切除术经验的原创文章。分析数据后,我们认为患者年龄不应成为诊断为食管癌的患者接受微创食管癌切除术的真正限制因素。

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本文引用的文献

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Prognostic impact of postoperative radiation in patients undergoing radical esophagectomy for pathologic lymph node positive esophageal cancer.术后放疗对病理淋巴结阳性食管癌根治性食管切除术后患者预后的影响。
Radiat Oncol. 2013 May 8;8:116. doi: 10.1186/1748-717X-8-116.
2
Outcomes after minimally invasive esophagectomy: review of over 1000 patients.微创食管切除术的结果:超过 1000 例患者的回顾。
Ann Surg. 2012 Jul;256(1):95-103. doi: 10.1097/SLA.0b013e3182590603.
3
Short-term outcomes following open versus minimally invasive esophagectomy for cancer in England: a population-based national study.英国开放性与微创食管癌切除术治疗癌症的短期预后:基于人群的全国性研究。
Ann Surg. 2012 Feb;255(2):197-203. doi: 10.1097/SLA.0b013e31823e39fa.
4
Oncologic efficacy is not compromised, and may be improved with minimally invasive esophagectomy.微创食管切除术不会影响肿瘤疗效,甚至可能改善肿瘤疗效。
J Am Coll Surg. 2011 Apr;212(4):560-6; discussion 566-8. doi: 10.1016/j.jamcollsurg.2010.12.042.
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Outcome of esophagectomy for cancer in elderly patients.老年食管癌患者的外科治疗结果。
Ann Thorac Surg. 2010 Sep;90(3):900-7. doi: 10.1016/j.athoracsur.2010.05.039.
6
Open versus minimally invasive esophagectomy: trends of utilization and associated outcomes in England.开放性与微创食管切除术:英国的应用趋势及相关结局。
Ann Surg. 2010 Aug;252(2):292-8. doi: 10.1097/SLA.0b013e3181dd4e8c.
7
Comparison of perioperative outcomes after combined thoracoscopic-laparoscopic esophagectomy and open Ivor-Lewis esophagectomy.比较胸腔镜联合腹腔镜与开胸 Ivor-Lewis 食管癌切除术的围手术期结果。
Am J Surg. 2010 May;199(5):594-8. doi: 10.1016/j.amjsurg.2010.01.005.
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Thoracolaparoscopy in the lateral position for esophageal cancer: the experience of a single institution with 112 consecutive patients.侧卧位胸腹腔镜食管癌手术:单中心 112 例连续病例经验
Surg Endosc. 2010 Oct;24(10):2407-14. doi: 10.1007/s00464-010-0963-8. Epub 2010 Mar 5.
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Ann Surg Oncol. 2010 Jun;17(6):1572-80. doi: 10.1245/s10434-010-0966-7. Epub 2010 Feb 24.
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