Takahashi Hironori, Matsubara Shigeki, Kuwata Tomoyuki, Ohkuchi Akihide, Mukoda Yukiko, Saito Koyomi, Usui Rie, Suzuki Mitsuaki
Department of Obstetrics and Gynecology, Jichi Medical University, Tochigi, Japan.
J Obstet Gynaecol Res. 2014 Apr;40(4):1114-7. doi: 10.1111/jog.12286. Epub 2014 Jan 15.
Various fetal or placental disorders cause Ballantyne's (mirror) syndrome. For the first time, we report a maternal manifestation of Ballantyne's syndrome occurring concomitantly with the development of fetal congenital mesoblastic nephroma (CMN). In a pregnant woman with a CMN fetus, lung edema, hypertension, hyperthyroidism, and high serum human chorionic gonadotrophin level occurred, all of which characterize maternal manifestation of Ballantyne's syndrome. The fetus and placenta were devoid of 'edema', lacking 'triple edema', and thus this condition was not diagnosed as Ballantyne's syndrome; however, we considered this condition as the maternal manifestation of Ballantyne's syndrome. We performed emergent cesarean section at 28 weeks. Delivery acutely ameliorated maternal symptoms. Tumor was resected and was confirmed as CMN. Maternal manifestations of Ballantyne's syndrome, such as lung edema and hypertension, can occur in a mother with fetal CMN even without fetal and/or placental edema. The clinical course of this patient may suggest an etiology of Ballantyne's syndrome.
多种胎儿或胎盘疾病可导致巴兰坦（镜像）综合征。我们首次报告了一例与胎儿先天性中胚层肾瘤（CMN）并发的巴兰坦综合征的母体表现。在一名怀有CMN胎儿的孕妇中，出现了肺水肿、高血压、甲状腺功能亢进和血清人绒毛膜促性腺激素水平升高，所有这些都是巴兰坦综合征母体表现的特征。胎儿和胎盘没有“水肿”，缺乏“三重水肿”，因此这种情况未被诊断为巴兰坦综合征；然而，我们认为这种情况是巴兰坦综合征的母体表现。我们在孕28周时进行了紧急剖宫产。分娩后母体症状迅速缓解。肿瘤被切除并确诊为CMN。即使没有胎儿和/或胎盘水肿，巴兰坦综合征的母体表现，如肺水肿和高血压，也可能发生在怀有胎儿CMN的母亲身上。该患者的临床病程可能提示了巴兰坦综合征的病因。
