Murphy Cara M, MacKillop James
Department of Psychology, University of Georgia, Athens, Georgia.
Alcohol Clin Exp Res. 2014 Apr;38(4):1134-42. doi: 10.1111/acer.12322. Epub 2014 Jan 15.
Mindfulness has been identified as a promising strategy for managing cravings for alcohol and other drugs, but little controlled experimental research has directly studied whether this approach is effective. The current study systematically examined the effects of an acute mindfulness manipulation on craving for alcohol during prolonged exposure to alcohol cues.
Heavy drinkers (N = 84, 50% male) underwent a prolonged alcohol cue exposure paradigm in a simulated bar environment and received either a mindfulness-based strategy, a distraction (DST)-based strategy (active control), or no strategy (passive control) to cope with alcohol cravings and discomfort associated with craving.
No baseline differences were present between conditions. Manipulation checks revealed that participants in the 2 active conditions reported using the recommended strategies. Across groups, the initial exposure to alcohol cues was associated with significant increases in craving, urge distress, and heart rate. Mixed analyses of variance on these indices following the experimental manipulation revealed significant differences based on condition over the course of the bar laboratory protocol. The DST strategy was significantly more effective at acutely reducing craving and urge distress than the other 2 conditions, which did not significantly differ from each other.
Contrary to our prediction, these findings suggest that an acute DSTstrategy is beneficial for coping with alcohol cravings. The potential importance of protracted mindfulness training to detect significant effects on in vivo craving, additional implications, and methodological considerations are discussed.
正念已被视为一种管理对酒精和其他药物渴望的有效策略,但很少有对照实验研究直接探究这种方法是否有效。本研究系统地考察了急性正念干预对长时间暴露于酒精线索期间酒精渴望的影响。
重度饮酒者(N = 84,50%为男性)在模拟酒吧环境中接受长时间的酒精线索暴露范式,并接受基于正念的策略、基于分心(DST)的策略(积极对照)或无策略(消极对照),以应对酒精渴望及与渴望相关的不适。
各条件之间在基线时无差异。操作检验显示,两个积极条件下的参与者报告使用了推荐策略。在所有组中,最初暴露于酒精线索与渴望、冲动痛苦和心率的显著增加相关。实验操作后对这些指标进行的混合方差分析显示,在酒吧实验室实验过程中,基于条件存在显著差异。DST策略在急性减少渴望和冲动痛苦方面比其他两个条件显著更有效,而这两个条件之间无显著差异。
与我们的预测相反,这些发现表明急性DST策略有助于应对酒精渴望。讨论了长期正念训练对检测体内渴望显著影响的潜在重要性、其他影响及方法学考量。