Sharma H S, Misra U K
Z Ernahrungswiss. 1987 Jun;26(2):116-24. doi: 10.1007/BF02019607.
The effect of maternal vitamin A restriction on the biochemical development of the lung in rats has been studied. The vitamin A status of dams has been varied by supplying low, medium and adequate amounts of vitamin A (6, 40 and 100 micrograms retinol/day/kg body weight, respectively) during pregnancy and suckling. The results demonstrate that the restricted supply of vitamin A to the mother affected the growth and development of the lung in parameters of tissue weight, DNA and protein levels and their biosynthesis from respective labelled precursors, RNA contents, cell number and cell size.
已对母体维生素A限制对大鼠肺生化发育的影响进行了研究。在怀孕和哺乳期间,通过分别提供低、中、适量的维生素A(分别为6、40和100微克视黄醇/天/千克体重)来改变母鼠的维生素A状态。结果表明,母体维生素A供应受限会影响肺的生长和发育,具体表现为组织重量、DNA和蛋白质水平及其从各自标记前体的生物合成、RNA含量、细胞数量和细胞大小等参数。