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欧洲癌症研究与治疗组织生活质量问卷-BR23乳腺癌特异性生活质量问卷:摩洛哥乳腺癌患者样本中的心理测量特性。

The European Organization for Research and Treatment of Cancer quality of life questionnaire-BR23 Breast Cancer-Specific Quality of Life Questionnaire: psychometric properties in a Moroccan sample of breast cancer patients.

作者信息

El Fakir Samira, Abda Naima, Bendahhou Karima, Zidouh Ahmed, Bennani Maria, Errihani Hassan, Benider Abdelatif, Bekkali Rachid, Nejjari Chakib

机构信息

Department of epidemiology and public health, Faculty of Medicine, University Sidi Mohammed Ben Abdellah, Fez, Morocco.

出版信息

BMC Res Notes. 2014 Jan 21;7:53. doi: 10.1186/1756-0500-7-53.

Abstract

BACKGROUND

Quality of life (QOL) and its measurement in cancer patients is becoming increasingly important. Breast cancer diagnosis and treatment are often associated with psychological distress and reduced QoL. In Arabic-speaking countries, QoL of patients with cancer is inadequately studied.The aim of this study was to test the reliability and validity of the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer (EORTC) Breast Cancer-Specific Quality of Life Questionnaire (QLQ-BR23).

METHODS

After translation and cross-cultural adaptation, the questionnaire was tested on breast cancer patients. The participants' number for the test and the retest were 105 and 37 respectively. Internal consistency was tested using Cronbach's alpha coefficient (α), the test-retest reliability using intraclass correlation coefficients (ICC). Construct validity was assessed by examining item-convergent and divergent validity.

RESULTS

The questionnaire was administered to 105 patients. The mean age of patients was 48 years (SD: 16), 62.9% were married. 68.6% of all participants lived in urban area.The average time to complete the QLQ- BR23 was 15 min. Cronbach's alpha coefficient, were all >0.7, with the exception of breast symptoms and arm symptoms. All items exceeded the 0.4 criterion for convergent validity except item 20 and 23 related to pain and skin problems in the affected breast respectively.

CONCLUSION

In general, the findings of this study indicated that the Moroccan Arabic version of the EORTC QLQ-BR23 is a reliable and valid supplementary measure of the QOL in breast cancer patients and can be used in clinical trials and studies of outcome research in oncology.

摘要

背景

癌症患者的生活质量(QOL)及其测量变得越来越重要。乳腺癌的诊断和治疗通常与心理困扰和生活质量下降有关。在讲阿拉伯语的国家,对癌症患者的生活质量研究不足。本研究的目的是测试欧洲癌症研究与治疗组织(EORTC)乳腺癌特异性生活质量问卷(QLQ-BR23)摩洛哥阿拉伯语版本的信度和效度。

方法

经过翻译和跨文化调适后,该问卷在乳腺癌患者中进行测试。测试和复测的参与者人数分别为105人和37人。使用Cronbach'sα系数(α)测试内部一致性,使用组内相关系数(ICC)测试重测信度。通过检查项目收敛效度和区分效度来评估结构效度。

结果

该问卷施用于105名患者。患者的平均年龄为48岁(标准差:16),62.9%已婚。所有参与者中有68.6%居住在城市地区。完成QLQ-BR23的平均时间为15分钟。除乳腺症状和手臂症状外,Cronbach'sα系数均>0.7。除分别与患侧乳房疼痛和皮肤问题相关的第20项和第23项外,所有项目均超过了收敛效度的0.4标准。

结论

总体而言,本研究结果表明,EORTC QLQ-BR23的摩洛哥阿拉伯语版本是乳腺癌患者生活质量的可靠且有效的补充测量工具,可用于肿瘤学临床试验和结局研究。

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