Jassim Ghufran, AlAnsari Ahmed
Department of Family Medicine, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen, Kingdom of Bahrain.
Quality Enhancement Office, Royal College of Surgeons in Ireland-Medical University of Bahrain, Busaiteen, Bahrain.
Neuropsychiatr Dis Treat. 2020 Dec 11;16:3045-3052. doi: 10.2147/NDT.S263190. eCollection 2020.
To evaluate the psychometric properties of the Arabic version of the EORTC QLQ-C30 and EORTC QLQ-BR23 questionnaires.
A cross-sectional study was carried out. A total of 337 subjects were recruited from the Oncology Centre in Bahrain and 239 consented to participation. The European Organization for Research and Treatment-QOL questionnaire and breast cancer-specific module (EORTC QLQ-C30 and QLQ-BR23) were used to measure the HRQOL among women with breast cancer. All statistical tests were performed using SPSS Version 20. The reliability of the EORTC QLQ-C30 and QLQ-BR23 questionnaires was examined using Cronbach's alpha test. The construct validity of both questionnaires was tested using the exploratory factor analysis.
Exploratory factor analysis results of EORTC QLQ-C30 showed that Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy was 0.878 and Bartlett's Test of Sphericity is <0.001. The extracted four-factor model explained 51.52% of the total variance. Relating to EORTC-QLQ-BR23, the KMO value was 0.735 and Bartlett's Test of Sphericity showed a significance of p<0.001 and extracted a three-factor model which explained a total variance of 46.05%. The Cronbach's alpha coefficient results for EORTC QLQ-C30 and QLQ BR-23 were 0.927and 0.844 respectively which reflects high internal consistency.
The EORTC QLQ-C30 and QLQ-BR23 questionnaires are feasible and promising instruments to measure the levels of HRQOL among Arabic-speaking women with breast cancer in future studies with some suggested modifications in some of the domains or items.
评估欧洲癌症研究与治疗组织生活质量问卷核心30条目版（EORTC QLQ-C30）和乳腺癌特异性模块（EORTC QLQ-BR23）阿拉伯语版本的心理测量特性。
开展一项横断面研究。从巴林肿瘤中心招募了337名受试者，其中239名同意参与。使用欧洲癌症研究与治疗组织生活质量问卷及乳腺癌特异性模块（EORTC QLQ-C30和QLQ-BR23）来测量乳腺癌女性的健康相关生活质量（HRQOL）。所有统计分析均使用SPSS 20版软件进行。采用克朗巴哈α检验来检验EORTC QLQ-C30和QLQ-BR23问卷的信度。使用探索性因子分析来检验两份问卷的结构效度。
EORTC QLQ-C30的探索性因子分析结果显示，Kaiser-Meyer-Olkin（KMO）抽样适当性度量为0.878，Bartlett球形检验<0.001。提取的四因子模型解释了总方差的51.52%。对于EORTC-QLQ-BR23，KMO值为0.735，Bartlett球形检验显示p<0.001具有显著性，并提取了一个三因子模型，该模型解释的总方差为46.05%。EORTC QLQ-C30和QLQ BR-23的克朗巴哈α系数结果分别为0.927和0.844，这反映出较高的内部一致性。
在未来针对讲阿拉伯语乳腺癌女性的研究中，EORTC QLQ-C30和QLQ-BR23问卷是测量健康相关生活质量水平可行且有前景的工具，不过在某些领域或条目上需进行一些建议的修改。
