Department of Pharmacy, Wuhan First Hospital, Wuhan 430022, Hubei, China.
Molecules. 2014 Jan 20;19(1):1250-7. doi: 10.3390/molecules19011250.
A new isocoumarin glycoside, 3R-(+)-5-O-[6'-O-acetyl]-α-D-glucopyranosyl-5-hydroxymellein (1), and a new phenylethanol glycoside, (-)-phenylethyl-8-O-α-L-rhamno-pyranoside (2), were isolated from the ethyl acetate extract of the fungus Xylaria sp. cfcc 87468, together with five known steroids, β-sitosterol (3), stigmast-4-en-3-one (4), ergosterol (5), (22E)-cholesta-4,6,8(14),22-tetraen-3-one (6), and 4α-methyl- ergosta-8(14),24(28)-dien-3β-ol (7). The structures of compounds 1 and 2 were elucidated by MS, extensive 1D and 2D NMR spectroscopy, and the circular dichroism (CD) spectroscopy.
从真菌 Xylaria sp. cfcc 87468 的乙酸乙酯提取物中分离得到了一种新的异香豆素糖苷，3R-(+)-5-O-[6'-O-乙酰基]-α-D-吡喃葡萄糖基-5-羟甲氧基色满（1），以及一种新的苯乙醇糖苷，(-)-苯乙基-8-O-α-L-鼠李吡喃糖苷（2），此外还有五种已知甾体化合物，β-谷甾醇（3）、豆甾-4-烯-3-酮（4）、麦角甾醇（5）、(22E)-胆甾-4,6,8(14),22-四烯-3-酮（6）和 4α-甲基-麦角甾-8(14),24(28)-二烯-3β-醇（7）。通过 MS、广泛的 1D 和 2D NMR 光谱以及圆二色性（CD）光谱确定了化合物 1 和 2 的结构。
