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假酸浆果实中的新糖苷。

New Glycosides from the Fruits of Nicandra physaloides.

作者信息

Liu Yan, Jiang Hai-Bing, Xu Zhen-Peng, Cheng Yan-Gang, Lv Shao-Wa, Yang Bing-You, Guo Hong-Wei, Kuang Hai-Xue

机构信息

Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China.

出版信息

Molecules. 2017 May 17;22(5):828. doi: 10.3390/molecules22050828.

DOI:10.3390/molecules22050828
PMID:28513563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6154662/
Abstract

Three new glycosides (-) and 15 known ones (-) were isolated and identified from the fruits of . The structures of these compounds were established by 1D and 2D NMR spectra and HR-ESI-MS. The compounds (-) were the first time isolated from the genus and they (except , , ) exhibited inhibitions on the NO release of LPS-induced RAW 264.7 cells with IC values from 26.9 to 47.5 μM.

摘要

从……的果实中分离并鉴定出三种新的糖苷（-）和15种已知的糖苷（-）。这些化合物的结构通过一维和二维核磁共振光谱以及高分辨电喷雾电离质谱得以确定。化合物（-）首次从……属中分离得到，并且它们（除了……、……、……）对脂多糖诱导的RAW 264.7细胞释放一氧化氮具有抑制作用，半数抑制浓度值在26.9至47.5微摩尔之间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf1/6154662/be740192141a/molecules-22-00828-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf1/6154662/e303941f5dd3/molecules-22-00828-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf1/6154662/be740192141a/molecules-22-00828-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf1/6154662/e303941f5dd3/molecules-22-00828-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf1/6154662/be740192141a/molecules-22-00828-g002.jpg

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Five withanolides from the leaves of Datura metel L. and their inhibitory effects on nitric oxide production.曼陀罗叶中的五种醉茄内酯及其对一氧化氮生成的抑制作用。
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Molecules. 2014 Jan 20;19(1):1250-7. doi: 10.3390/molecules19011250.
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Antioxidant glucosylated caffeoylquinic acid derivatives in the invasive tropical soda apple, Solanum viarum.入侵热带苏打苹果（Solanum viarum）中的抗氧化葡糖基化咖啡酰奎宁酸衍生物。
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Acteoside and 6-O-acetylacteoside downregulate cell adhesion molecules induced by IL-1beta through inhibition of ERK and JNK in human vascular endothelial cells.毛蕊花糖苷和 6-O-乙酰毛蕊花糖苷通过抑制人血管内皮细胞中 ERK 和 JNK 下调由 IL-1β诱导的细胞黏附分子。
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Phenylethanoid glycosides from Lantana fucata with in vitro anti-inflammatory activity.来自黄花马缨丹具有体外抗炎活性的苯乙醇苷类化合物。
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