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优化双酚 A 二甲基丙烯酸酯/三乙二醇二甲基丙烯酸酯牙科树脂体系中季铵基二甲基丙烯酸酯单体的浓度以提高抗菌活性和机械性能。

Optimizing the concentration of quaternary ammonium dimethacrylate monomer in bis-GMA/TEGDMA dental resin system for antibacterial activity and mechanical properties.

机构信息

College of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, China.

出版信息

J Mater Sci Mater Med. 2014 May;25(5):1387-93. doi: 10.1007/s10856-014-5156-x. Epub 2014 Jan 22.

Abstract

Four novel quaternary ammonium dimethacrylate monomers named IMQ (side alkyl chain length from 12 to 18) were synthesized with the aim to synthesize dental resin with antibacterial activity. All of IMQs were added into bis-GMA/TEGDMA dental resin system with a series of mass ratio (5, 10, and 20 wt%), double bond conversion (DC), flexural strength (FS), modulus of elasticity (FM) and biofilm formation inhibitory effect were studied. According to the results of DC, FS, FM, and the biofilm inhibitory effect, IMQ-16 containing polymer had the best comprehensive properties, and the optimal concentration of IMQ-16 in bis-GMA/TEGDMA dental resin would be in the range of 5-10 wt%.

摘要

四种新型季铵盐二甲基丙烯酸酯单体,命名为 IMQ(侧链烷基长度为 12 至 18),被合成出来,旨在合成具有抗菌活性的牙科用树脂。所有的 IMQ 都以一系列质量比(5、10 和 20wt%)加入到双酚 G 甲基丙烯酸缩水甘油酯/三乙二醇二甲基丙烯酸酯牙科树脂体系中,双键转化率(DC)、弯曲强度(FS)、弹性模量(FM)和生物膜形成抑制效果都进行了研究。根据 DC、FS、FM 和生物膜抑制效果的结果,含有 IMQ-16 的聚合物具有最好的综合性能,IMQ-16 在双酚 G 甲基丙烯酸缩水甘油酯/三乙二醇二甲基丙烯酸酯牙科树脂中的最佳浓度范围为 5-10wt%。

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