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小腿淤积性皮炎皮肤的ATP酶染色表皮片制剂中朗格汉斯细胞的密度。

Density of Langerhans' cells in ATPase stained epidermal sheet preparations from stasis dermatitis skin of the lower leg.

作者信息

Bahmer F A, Lesch H

机构信息

Department of Dermatology, University Hospital Homburg, Saar, FRG.

出版信息

Acta Derm Venereol. 1987;67(4):301-4.

PMID:2445147
Abstract

The density of Langerhans' cells (LC) stained with ATPase was determined in epidermal sheet preparations in skin specimens from patients with stasis dermatitis of the lower leg. Their density was highest in areas adjacent to manifest stasis dermatitis areas. Clinically diseased skin contained less LC than the adjacent areas, but still more than skin from control patients without venous insufficiency. The increased number of ATPase positive cells within and around stasis dermatitis skin might contribute to the high number of contact allergies observed in this patient group because of the antigen presenting capacity of these cells.

摘要

用ATP酶染色法测定小腿淤积性皮炎患者皮肤标本表皮片制备物中朗格汉斯细胞(LC)的密度。其密度在与明显淤积性皮炎区域相邻的部位最高。临床上患病皮肤中的LC比相邻区域少,但仍比无静脉功能不全的对照患者的皮肤多。由于这些细胞的抗原呈递能力,淤积性皮炎皮肤内及周围ATP酶阳性细胞数量的增加可能是该患者组中观察到的接触性过敏高发的原因。

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