在羊体内传播经典羊瘙痒病的证据。
Evidence of in utero transmission of classical scrapie in sheep.
机构信息
Animal Health and Veterinary Laboratories Agency (AHVLA) Weybridge, Addlestone, Surrey, United Kingdom.
出版信息
J Virol. 2014 Apr;88(8):4591-4. doi: 10.1128/JVI.03264-13. Epub 2014 Jan 22.
Abstract
Classical scrapie is one of the transmissible spongiform encephalopathies (TSEs), a group of fatal infectious diseases that affect the central nervous system (CNS). Classical scrapie can transmit laterally from ewe to lamb perinatally or between adult animals. Here we report detection of infectivity in tissues of an unborn fetus, providing evidence that in utero transmission of classical scrapie is also possible.
摘要
经典绵羊痒病是传染性海绵状脑病（TSEs）之一，这是一组影响中枢神经系统（CNS）的致命传染病。经典绵羊痒病可以在围产期从母羊横向传播给羔羊，或在成年动物之间传播。在这里，我们报告了在未出生胎儿组织中检测到传染性，这为经典绵羊痒病的宫内传播也是可能的提供了证据。
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