Jung Su-Jin, Park Soo-Hyun, Choi Eun-Kyung, Cha Youn-Soo, Cho Baik-Hwan, Kim Young-Gon, Kim Min-Gul, Song Won O, Park Tae-Sun, Ko Jae-Ki, So Byung-Ok, Chae Soo-Wan
1 Clinical Trial Center for Functional Foods, Chonbuk National University Hospital , Jeonju, Republic of Korea.
J Med Food. 2014 Jan;17(1):161-71. doi: 10.1089/jmf.2013.3042.
The prevalence of metabolic syndrome, hypertension, and diabetes has been increasing rapidly in Korea. The rate of increase has paralleled the replacement of Korean traditional diets (KTD), which emphasize vegetables and fermented foods, with western style dietary patterns that are rich in animal foods and saturated fat. We aimed to investigate the efficacy of the KTD in controlling fasting plasma glucose, blood pressure, and cardiovascular disease risk factors in hypertensive and type 2 diabetic (T2D) patients. Forty-one patients (61.8±1.5 years) who were taking medications prescribed for respective diseases were recruited from the Chonbuk National University Hospital for participation in a 12-week, parallel, controlled clinical trial. The control group (n=20) was advised to "eat as usual," whereas the experimental KTD diet group (n=21) was fed the KTD three times a day for 12 weeks. At the end of the trial, both groups had lower body mass index, % body fat, and waist-hip ratio compared to the baseline values (P<.05). Compared to the control group, the KTD group had a greater mean change (P<.05) from the baseline for glycated hemoglobin (HbA₁c) (-0.72% vs. -0.25%) and heart rate (-7.1 vs. +1.6). Regular consumption of the KTD for 12 weeks by hypertensive and T2D patients resulted in favorable changes in cardiovascular risk factors.
在韩国，代谢综合征、高血压和糖尿病的患病率一直在迅速上升。其上升速度与韩国传统饮食（KTD）被富含动物性食物和饱和脂肪的西式饮食模式所取代的情况同步，韩国传统饮食强调蔬菜和发酵食品。我们旨在研究韩国传统饮食对高血压和2型糖尿病（T2D）患者空腹血糖、血压及心血管疾病危险因素的控制效果。从全北国立大学医院招募了41名正在服用各自疾病规定药物的患者（年龄61.8±1.5岁），参与一项为期12周的平行对照临床试验。对照组（n = 20）被建议“照常饮食”，而实验性韩国传统饮食组（n = 21）在12周内每天食用三次韩国传统饮食。在试验结束时，与基线值相比，两组的体重指数、体脂百分比和腰臀比均降低（P<0.05）。与对照组相比，韩国传统饮食组糖化血红蛋白（HbA₁c）（-0.72%对-0.25%）和心率（-7.1对+1.6）从基线的平均变化更大（P<0.05）。高血压和2型糖尿病患者连续12周规律食用韩国传统饮食可使心血管危险因素发生有利变化。
