Husson O, Oerlemans S, Mols F, Smeets R E H, Poortmans P M, van de Poll-Franse L V
Center of Research on Psychology in Somatic diseases (CoRPS), Department of Medical and Clinical Psychology, Tilburg University , The Netherlands.
Acta Oncol. 2014 Jul;53(7):917-26. doi: 10.3109/0284186X.2013.879201. Epub 2014 Jan 23.
Appropriate information provision is an important determinant of patient satisfaction and might also affect health-related quality of life (HRQoL) of cancer patients. The aim of this study was to examine the relationship between perceived information provision at baseline and HRQoL, anxiety and depression among lymphoma patients two years later.
This study is part of a longitudinal, population-based survey among all lymphoma patients diagnosed between 1999 and 2009 as registered in the Eindhoven Cancer Registry (southern part of The Netherlands). Patients between six months and 10 years after diagnoses received the first questionnaire including the EORTC QLQ-INFO25, EORTC QLQ-C30 and HADS at baseline (T1) and the second two years later (T2). All analyses are stratified for time since diagnosis (< 2 and ≥ 2 years since diagnosis).
At baseline 69% of the patients (n = 1186) responded, at T2 355 (30%) patients responded. For patients < 2 years since diagnosis, receiving more medical test information was associated with higher levels of cognitive functioning (ß = 0.46; p = 0.04) and lower levels of anxiety (ß = -0.41; p = 0.04) at baseline, no prospective relationships were found. For patients ≥ 2 years since diagnosis, receiving more medical test information (ß = 0.20; p = 0.03) was associated with better emotional functioning, while receiving more treatment information was associated with worse emotional functioning (ß = -0.21; p = 0.04). Among this group, satisfaction with the received information was associated with better functioning (ß ranging from -0.15 to -0.33; all p < 0.05) at baseline, and these relationships remained significant prospectively for physical (ß = -0.13; p = 0.02) and emotional functioning (ß = -0.13; p = 0.04) only. Stability of satisfaction with received information over time was associated with better emotional (ß = -0.13) and better cognitive functioning (ß = -0.09; p < 0.05) at T2.
The present study showed that satisfaction with received information among lymphoma patients was associated with better HRQoL at baseline (only for patients ≥ 2 years since diagnosis), but not at follow-up when corrected for baseline HRQoL.
提供恰当的信息是患者满意度的一个重要决定因素，也可能影响癌症患者的健康相关生活质量（HRQoL）。本研究的目的是调查基线时感知到的信息提供情况与两年后淋巴瘤患者的HRQoL、焦虑和抑郁之间的关系。
本研究是一项基于人群的纵向调查的一部分，研究对象为1999年至2009年在埃因霍温癌症登记处（荷兰南部）登记的所有淋巴瘤患者。诊断后6个月至10年的患者在基线时（T1）接受第一份问卷，包括欧洲癌症研究与治疗组织（EORTC）的QLQ - INFO25、QLQ - C30和医院焦虑抑郁量表（HADS），两年后（T2）接受第二份问卷。所有分析按诊断后的时间分层（诊断后<2年和≥2年）。
基线时69%的患者（n = 1186）做出了回应，T2时355名（30%）患者做出了回应。对于诊断后<2年的患者，在基线时，获得更多医学检查信息与较高水平的认知功能（β = 0.46；p = 0.04）和较低水平的焦虑（β = -0.41；p = 0.04）相关，未发现前瞻性关系。对于诊断后≥2年的患者，获得更多医学检查信息（β = 0.20；p = 0.03）与更好的情绪功能相关，而获得更多治疗信息与更差的情绪功能相关（β = -0.21；p = 0.04）。在这组患者中，对所获信息的满意度在基线时与更好的功能相关（β范围为 -0.15至 -0.33；所有p < 0.05），并且这些关系仅在身体（β = -0.13；p = 0.02）和情绪功能（β = -0.13；p = 0.04）方面前瞻性地保持显著。随着时间推移，对所获信息满意度的稳定性与T2时更好的情绪（β = -0.13）和更好的认知功能（β = -0.09；p < 0.05）相关。
本研究表明，淋巴瘤患者对所获信息的满意度在基线时（仅针对诊断后≥2年的患者）与更好的HRQoL相关，但在对基线HRQoL进行校正后的随访中则不然。
