Mattoo Surendra Kumar, Nebhinani Naresh, Aggarwal Munish, Basu Debasish, Kulhara Parmanand
Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
All India Institute of Medical Science, Jodhpur, Rajasthan, India.
Ind Psychiatry J. 2013 Jan;22(1):60-4. doi: 10.4103/0972-6748.123631.
Substance abuse, alcohol in particular, is associated with increased risk of diabetes and metabolic syndrome (MS). The relationship between the substance abuse and MS is complex and the literature is sparse.
The present research was aimed to study the prevalence and predictors of MS among outpatients with substance dependence.
Patients with substance dependence were recruited from a deaddiction center in North India, who attended outpatient clinic from 1(st) January, 2010-31(st) December, 2010. MS was assessed using International Diabetes Federation (IDF) criteria.
Out of 250 subjects, 34 (13.6%) of the subjects met the IDF criteria for MS and highest being in alcohol group (21.6%). The commonest abnormality was increased triglycerides (TG; 54%) and increased waist circumference (36.8%). Age, body weight, body mass index, and obesity were significant predictor of MS.
MS was highest in subjects with alcohol dependence with the commonest abnormality of TG and blood pressure. Hence, routine screening is advisable in this population to address emerging MS.
物质滥用，尤其是酒精滥用，与糖尿病和代谢综合征（MS）风险增加相关。物质滥用与MS之间的关系复杂，相关文献较少。
本研究旨在探讨物质依赖门诊患者中MS的患病率及预测因素。
从印度北部一家戒毒中心招募物质依赖患者，这些患者于2010年1月1日至2010年12月31日在门诊就诊。采用国际糖尿病联盟（IDF）标准评估MS。
250名受试者中，34名（13.6%）符合MS的IDF标准，其中酒精组患病率最高（21.6%）。最常见的异常是甘油三酯（TG）升高（54%）和腰围增加（36.8%）。年龄、体重、体重指数和肥胖是MS的显著预测因素。
酒精依赖患者中MS患病率最高，最常见的异常是TG和血压异常。因此，建议对该人群进行常规筛查以应对新发的MS。
