动脉导管未闭封堵术中对乙酰氨基酚的有效性、安全性及血药浓度监测：病例系列
Paracetamol effectiveness, safety and blood level monitoring during patent ductus arteriosus closure: a case series.
作者信息
Kessel Irena, Waisman Dan, Lavie-Nevo Karen, Golzman Marcelo, Lorber Avraham, Rotschild Avi
机构信息
Department of Neonatology, Carmel Medical Center , Haifa, Israel .
出版信息
J Matern Fetal Neonatal Med. 2014 Nov;27(16):1719-21. doi: 10.3109/14767058.2013.871630. Epub 2014 Feb 7.
Paracetamol was reported to be effective for patent ductus arteriosus (PDA) closure. We present a case series of PDA closure by paracetamol in seven premature infants. During the treatment, paracetamol blood levels did not exceed the recommended levels for analgesia and hyperthermia in six tested infants. None of the patients demonstrated significant disturbances of liver function.
据报道，对乙酰氨基酚对动脉导管未闭（PDA）闭合有效。我们展示了一组7例早产儿使用对乙酰氨基酚闭合PDA的病例系列。在治疗过程中，6例接受检测的婴儿的对乙酰氨基酚血药浓度未超过镇痛和退热的推荐水平。所有患者均未出现明显的肝功能紊乱。
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