Burda Piotr, Gomółka Ewa, Winnicka Renata, Olszowy Zofia, Madej Teresa, Wendeker Beata, Sommerfeld Karina, Zajko Ewa
Ośrodek Kontroli Zatruć, Warszawa.
Pracownia Toksykologii Analitycznej i Terapii Monitorowanej, Katedra Toksykologii i Chorób Srodowiskowych, Uniwersytet Jagielloński Collegium Medium, Kraków.
Przegl Lek. 2013;70(8):490-9.
There are 12 centers of acute poisoning treatment and 9 round the clock toxicological laboratories. Most of the laboratories access evidence of activity run by National Clinical Toxicology Consultant. The paper presents actual status of medical toxicology laboratories in Poland and summarizes activity of the laboratories in the year 2012. In 2012 toxicological laboratories reported 113,719 assays. There were diagnosed 63.8% men and 34.8% women. The toxicological laboratories determine most substances and markers of exposition to chemical compounds important for diagnosis and treatment of acute poisonings (i.e. ethanol, methanol, ethylene glycol, acetaminophen, salicylates, anticonvulsants, carboxyhemoglobin, methemoglobin). There is not possible to determine heavy metals, all medicines and "designed" drugs of abuse in all laboratories. Limited access to reference methods, that enable to confirm results obtained by screening methods (immunological cassette and strip tests) is also a problem.
波兰有12个急性中毒治疗中心和9个全天候运作的毒理学实验室。大多数实验室可获取由国家临床毒理学顾问开展的活动证据。本文介绍了波兰医学毒理学实验室的实际状况,并总结了这些实验室2012年的活动情况。2012年,毒理学实验室报告了113,719次检测。诊断出男性占63.8%,女性占34.8%。毒理学实验室可测定对急性中毒的诊断和治疗至关重要的大多数化合物的物质和暴露标志物(即乙醇、甲醇、乙二醇、对乙酰氨基酚、水杨酸盐、抗惊厥药、碳氧血红蛋白、高铁血红蛋白)。并非所有实验室都能测定重金属、所有药物和“特制”滥用药物。获得参考方法的途径有限,而参考方法能够确认通过筛查方法(免疫检测盒和试纸检测)获得的结果,这也是一个问题。