Hari R, Joutsiniemi S L, Sarvas J
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland.
Electroencephalogr Clin Neurophysiol. 1988 Jan-Feb;71(1):64-72. doi: 10.1016/0168-5597(88)90020-2.
Spatial resolution of magnetoencephalography (MEG) was studied by computer simulations using a spherical conductor model for the head. The accuracy obtainable in the absolute location of a dipole was found by calculating the confidence limits for source location in 3 dimensions. The accuracy in determining the relative locations of two sources was estimated by calculating the smallest shift in source location that could be detected with statistical significance. The results were used to illustrate the dependence of spatial resolution on several factors including noise, source depth, source strength, flux transformer configuration and the choice of the measurement locations. Under optimal conditions, separations of a couple of millimeters in superficial non-simultaneous sources can be detected, whereas for deeper sources the resolution is worse.
使用头部的球形导体模型通过计算机模拟研究了脑磁图（MEG）的空间分辨率。通过计算三维空间中源位置的置信限，得出了偶极子绝对位置可达到的精度。通过计算可检测到的具有统计学意义的源位置最小偏移量，估计了确定两个源相对位置的精度。结果用于说明空间分辨率对几个因素的依赖性，这些因素包括噪声、源深度、源强度、磁通变换器配置以及测量位置的选择。在最佳条件下，可以检测到浅表非同时源中几毫米的间距，而对于较深的源，分辨率则较差。
