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脑动脉树的形态测量、地理和区域特征

Morphometric, geographic, and territorial characterization of brain arterial trees.

作者信息

Mut Fernando, Wright Susan, Ascoli Giorgio A, Cebral Juan R

机构信息

Center for Computational Fluid Dynamics, College of Sciences, George Mason University, 4400 University Drive, MSN 3F3 Fairfax, Virginia 22030, USA.

出版信息

Int J Numer Method Biomed Eng. 2014 Jul;30(7):755-66. doi: 10.1002/cnm.2627. Epub 2014 Jan 27.

DOI:10.1002/cnm.2627
PMID:24470176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4082472/
Abstract

Morphometric information of the brain vascularization is valuable for a variety of clinical and scientific applications. In particular, this information is important when creating arterial tree models for imposing boundary conditions in numerical simulations of the brain hemodynamics. The purpose of this work is to provide quantitative descriptions of arterial branches, bifurcation patterns, shape, and geographical distribution of the arborization of the main cerebral arteries as well as estimations of the corresponding vascular territories. For this purpose, subject-specific digital reconstructions of the brain vascular network created from 3T magnetic resonance angiography images of healthy volunteers are used to derive population-averaged morphometric characteristics of the cerebral arterial trees. Copyri

摘要

脑血管形成的形态测量信息对于各种临床和科学应用都很有价值。特别是,在创建动脉树模型以在脑血流动力学的数值模拟中施加边界条件时,这些信息非常重要。这项工作的目的是提供对大脑主要动脉分支、分叉模式、形状和分支的地理分布的定量描述,以及对相应血管区域的估计。为此,利用从健康志愿者的3T磁共振血管造影图像创建的特定受试者脑血管网络数字重建,来推导脑动脉树的总体平均形态测量特征。版权所有

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本文引用的文献

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Digital reconstruction and morphometric analysis of human brain arterial vasculature from magnetic resonance angiography.基于磁共振血管成像的人脑动脉血管的数字重建与形态计量分析。
Neuroimage. 2013 Nov 15;82:170-81. doi: 10.1016/j.neuroimage.2013.05.089. Epub 2013 May 28.
2
A computational approach to generate concurrent arterial networks in vascular territories.一种生成血管区域内并发动脉网络的计算方法。
Int J Numer Method Biomed Eng. 2013 May;29(5):601-14. doi: 10.1002/cnm.2547. Epub 2013 Apr 10.
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Digital reconstructions of neuronal morphology: three decades of research trends.神经元形态的数字重建:三十年研究趋势
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Which diameter and angle rule provides optimal flow patterns in a coronary bifurcation?哪种直径和角度的血管分叉支架能够提供最佳的冠脉血流模式?
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