• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

X 射线相衬成像:从同步加速器到医院。

X-ray phase imaging: from synchrotron to hospital.

机构信息

Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, , 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan.

出版信息

Philos Trans A Math Phys Eng Sci. 2014 Jan 27;372(2010):20130023. doi: 10.1098/rsta.2013.0023. Print 2014 Mar 6.

DOI:10.1098/rsta.2013.0023
PMID:24470409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3900032/
Abstract

With the aim of clinical applications of X-ray phase imaging based on Talbot-Lau-type grating interferometry to joint diseases and breast cancer, machines employing a conventional X-ray generator have been developed and installed in hospitals. The machine operation especially for diagnosing rheumatoid arthritis is described, which relies on the fact that cartilage in finger joints can be depicted with a dose of several milligray. The palm of a volunteer observed with 19 s exposure (total scan time: 32 s) is reported with a depicted cartilage feature in joints. This machine is now dedicated for clinical research with patients.

摘要

为了将基于泰伯-劳型光栅干涉法的 X 射线相位成像技术应用于关节疾病和乳腺癌的临床诊断,已经开发并在医院中安装了使用传统 X 射线发生器的设备。本文介绍了一种专门用于诊断类风湿关节炎的设备操作方法,其原理是可以用几毫戈瑞的剂量来描绘手指关节的软骨。本文报告了对志愿者手掌进行 19 秒曝光(总扫描时间:32 秒)的结果,其中显示了关节处软骨的特征。该设备目前正用于对患者进行临床研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e01/3900032/c787317860f4/rsta20130023-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e01/3900032/73fa4f6fc2a8/rsta20130023-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e01/3900032/c787317860f4/rsta20130023-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e01/3900032/73fa4f6fc2a8/rsta20130023-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e01/3900032/c787317860f4/rsta20130023-g2.jpg

相似文献

1
X-ray phase imaging: from synchrotron to hospital.X 射线相衬成像:从同步加速器到医院。
Philos Trans A Math Phys Eng Sci. 2014 Jan 27;372(2010):20130023. doi: 10.1098/rsta.2013.0023. Print 2014 Mar 6.
2
Imaging evaluation of the cartilage in rheumatoid arthritis patients with an x-ray phase imaging apparatus based on Talbot-Lau interferometry.基于泰伯-劳厄干涉仪的 X 射线相衬成像仪在类风湿关节炎患者软骨成像评估中的应用。
Sci Rep. 2020 Apr 16;10(1):6561. doi: 10.1038/s41598-020-63155-9.
3
A preclinical Talbot-Lau prototype for x-ray dark-field imaging of human-sized objects.用于人体大小物体的 X 射线暗场成像的临床前 Talbot-Lau 原型。
Med Phys. 2018 Jun;45(6):2565-2571. doi: 10.1002/mp.12889. Epub 2018 Apr 27.
4
Technical Note: Single-shot phase retrieval method for synchrotron-based high-energy x-ray grating interferometry.技术说明:基于同步加速器的高能 X 射线光栅干涉术的单次相位恢复方法。
Med Phys. 2019 Mar;46(3):1317-1322. doi: 10.1002/mp.13399. Epub 2019 Feb 13.
5
Increasing the field of view in grating based X-ray phase contrast imaging using stitched gratings.使用拼接光栅扩大基于光栅的X射线相衬成像中的视野。
J Xray Sci Technol. 2016 Mar 17;24(3):379-88. doi: 10.3233/XST-160552.
6
Four-dimensional X-ray phase tomography with Talbot interferometry and white synchrotron radiation: dynamic observation of a living worm.基于塔尔博特干涉术和白色同步辐射的四维X射线相位断层扫描:活蠕虫的动态观察
Opt Express. 2011 Apr 25;19(9):8423-32. doi: 10.1364/OE.19.008423.
7
Predicting fringe visibility in dual-phase grating interferometry with polychromatic X-ray sources.用多色 X 射线源预测双相位光栅干涉中的边缘可见度。
J Xray Sci Technol. 2020;28(6):1055-1067. doi: 10.3233/XST-200726.
8
Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry.基于 X 射线泰伯-劳(Talbot-Lau)干涉差分相衬的尸体和活体人关节成像。
Z Med Phys. 2013 Sep;23(3):222-7. doi: 10.1016/j.zemedi.2012.11.004. Epub 2012 Dec 6.
9
X-ray phase imaging reaching clinical uses.X 射线相衬成像达到临床应用。
Phys Med. 2020 Nov;79:93-102. doi: 10.1016/j.ejmp.2020.11.003. Epub 2020 Nov 17.
10
High-speed X-ray phase imaging and X-ray phase tomography with Talbot interferometer and white synchrotron radiation.利用塔尔博特干涉仪和白色同步辐射进行高速X射线相成像和X射线相断层扫描。
Opt Express. 2009 Jul 20;17(15):12540-5. doi: 10.1364/oe.17.012540.

引用本文的文献

1
Assessment of CA4+ Impact on Mechanical Properties of Articular Cartilage.评估CA4+对关节软骨力学性能的影响。
Materials (Basel). 2025 Jun 21;18(13):2943. doi: 10.3390/ma18132943.
2
Fabrication of X-ray absorption gratings by centrifugal deposition of bimodal tungsten particles in high aspect ratio silicon templates.离心沉积双峰钨颗粒在高纵横比硅模板中制备 X 射线吸收光栅。
Sci Rep. 2022 Mar 30;12(1):5405. doi: 10.1038/s41598-022-08222-z.
3
Dark-field computed tomography reaches the human scale.暗场计算机断层扫描达到人体尺度。

本文引用的文献

1
Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry.基于 X 射线泰伯-劳(Talbot-Lau)干涉差分相衬的尸体和活体人关节成像。
Z Med Phys. 2013 Sep;23(3):222-7. doi: 10.1016/j.zemedi.2012.11.004. Epub 2012 Dec 6.
2
Experimental results from a preclinical X-ray phase-contrast CT scanner.临床前 X 射线相衬 CT 扫描仪的实验结果。
Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15691-6. doi: 10.1073/pnas.1207503109. Epub 2012 Sep 10.
3
The first analysis and clinical evaluation of native breast tissue using differential phase-contrast mammography.
Proc Natl Acad Sci U S A. 2022 Feb 22;119(8). doi: 10.1073/pnas.2118799119.
4
Synchrotron Radiation-based X-ray phase-contrast imaging of the aortic walls in acute aortic dissection.基于同步辐射的急性主动脉夹层主动脉壁X射线相衬成像
JVS Vasc Sci. 2020 Jul 16;1:81-91. doi: 10.1016/j.jvssci.2020.06.002. eCollection 2020.
5
Current Trends in Integration of Nondestructive Testing Methods for Engineered Materials Testing.当前工程材料测试中无损检测方法集成的趋势。
Sensors (Basel). 2021 Sep 15;21(18):6175. doi: 10.3390/s21186175.
6
X-ray dark-field radiography for in situ gout diagnosis by means of an ex vivo animal study.X 射线暗场射线照相术用于通过离体动物研究进行原位痛风诊断。
Sci Rep. 2021 Sep 24;11(1):19021. doi: 10.1038/s41598-021-98151-0.
7
Fabrication of X-ray Gratings for Interferometric Imaging by Conformal Seedless Gold Electroplating.通过保形无籽金电镀制造用于干涉成像的X射线光栅。
Micromachines (Basel). 2021 May 7;12(5):517. doi: 10.3390/mi12050517.
8
X-ray Phase Contrast osteo-articular imaging: a pilot study on cadaveric human hands.X 射线相衬骨与关节成像:对人尸手的初步研究。
Sci Rep. 2020 Feb 5;10(1):1911. doi: 10.1038/s41598-020-58168-3.
9
Impact of a single distance phase retrieval algorithm on spatial resolution in X-ray inline phase sensitive imaging.单距离相位恢复算法对X射线同轴相位敏感成像中空间分辨率的影响。
Biomed Spectrosc Imaging. 2019 Jul 9;8(1-2):29-40. doi: 10.3233/BSI-190186. Epub 2019 Feb 22.
10
Implementation of a double-grating interferometer for phase-contrast computed tomography in a conventional system nanotom m.在传统的纳米断层扫描系统 nanotom m 中实现用于相衬计算机断层扫描的双光栅干涉仪。
APL Bioeng. 2018 Jan 26;2(1):016106. doi: 10.1063/1.5022184. eCollection 2018 Mar.
利用差分相衬乳腺摄影术对原生乳腺组织进行的首次分析和临床评估。
Invest Radiol. 2011 Dec;46(12):801-6. doi: 10.1097/RLI.0b013e31822a585f.
4
X-ray phase imaging with a grating interferometer.使用光栅干涉仪的X射线相成像
Opt Express. 2005 Aug 8;13(16):6296-304. doi: 10.1364/opex.13.006296.
5
Hard-X-ray dark-field imaging using a grating interferometer.使用光栅干涉仪的硬X射线暗场成像。
Nat Mater. 2008 Feb;7(2):134-7. doi: 10.1038/nmat2096. Epub 2008 Jan 20.
6
Mammography with synchrotron radiation: phase-detection techniques.同步辐射乳腺摄影:相位检测技术
Radiology. 2000 Apr;215(1):286-93. doi: 10.1148/radiology.215.1.r00ap10286.