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使用拼接光栅扩大基于光栅的X射线相衬成像中的视野。

Increasing the field of view in grating based X-ray phase contrast imaging using stitched gratings.

作者信息

Meiser J, Willner M, Schröter T, Hofmann A, Rieger J, Koch F, Birnbacher L, Schüttler M, Kunka D, Meyer P, Faisal A, Amberger M, Duttenhofer T, Weber T, Hipp A, Ehn S, Walter M, Herzen J, Schulz J, Pfeiffer F, Mohr J

机构信息

Institute of Microstructure Technology, Karlsruhe Institute of Technology Eggenstein-Leopoldshafen, Germany.

Department of Physics and Institute of Medical Engineering, Technische Universität München, Garching, Germany.

出版信息

J Xray Sci Technol. 2016 Mar 17;24(3):379-88. doi: 10.3233/XST-160552.

Abstract

Grating based X-ray differential phase contrast imaging (DPCI) allows for high contrast imaging of materials with similar absorption characteristics. In the last years' publications, small animals or parts of the human body like breast, hand, joints or blood vessels have been studied. Larger objects could not be investigated due to the restricted field of view limited by the available grating area. In this paper, we report on a new stitching method to increase the grating area significantly: individual gratings are merged on a carrier substrate. Whereas the grating fabrication process is based on the LIGA technology (X-ray lithography and electroplating) different cutting and joining methods have been evaluated. First imaging results using a 2×2 stitched analyzer grating in a Talbot-Lau interferometer have been generated using a conventional polychromatic X-ray source. The image quality and analysis confirm the high potential of the stitching method to increase the field of view considerably.

摘要

基于光栅的X射线微分相衬成像(DPCI)能够对具有相似吸收特性的材料进行高对比度成像。在过去几年的文献中,已对小动物或人体的某些部位(如乳房、手部、关节或血管)展开了研究。由于可用光栅面积限制了视野范围,较大的物体无法进行研究。在本文中,我们报告了一种显著增加光栅面积的新拼接方法:将单个光栅合并在载体基板上。鉴于光栅制造工艺基于LIGA技术(X射线光刻和电镀),已对不同的切割和连接方法进行了评估。使用传统的多色X射线源,在Talbot-Lau干涉仪中利用2×2拼接分析光栅生成了首批成像结果。图像质量和分析证实了拼接方法在大幅增加视野方面的巨大潜力。

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