小鼠脑中两种形式的pp60c-src的发育表达。
Developmental expression of two forms of pp60c-src in mouse brain.
作者信息
Wiestler O D, Walter G
机构信息
Department of Pathology, University of California, San Diego, La Jolla 92093.
出版信息
Mol Cell Biol. 1988 Jan;8(1):502-4. doi: 10.1128/mcb.8.1.502-504.1988.
Abstract
The expression during mouse development of two forms of protein-tyrosine kinase pp60c-src, pp60 and pp60+, was investigated. At embryonic day 9 (E9), only pp60 was detected in whole-brain lysates. A trace of pp60+ was first seen at E10. In E18 embryos and in adults, pp60+ was the predominant form of pp60c-src in forebrain and midbrain lysates.
摘要
研究了两种蛋白酪氨酸激酶pp60c-src的形式，即pp60和pp60+在小鼠发育过程中的表达情况。在胚胎第9天（E9），全脑裂解物中仅检测到pp60。在E10首次发现微量的pp60+。在E18胚胎和成年小鼠中，pp60+是前脑和中脑裂解物中pp60c-src的主要形式。
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