Jin Peng-fei, Zuo Wen-jian, Guo Zhi-kai, Mei Wen-li, Dai Hao-fu
College of Environment and Plant Protection, Hainan University, 570228 Haikou, China.
Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, 571101 Haikou, China.
Yao Xue Xue Bao. 2013 Nov;48(11):1688-91.
To investigate the chemical constituents of the endophytic fungus Penicillium sp. FJ-1 of Ceriops tagal, the chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20. Their structures were elucidated on the basis of spectroscopic analysis. Their antibacterial activity was tested by paper disco diffusion method. Two compounds were isolated and identified as 7-hydroxy-deoxytalaroflavone (1), and deoxytalaroflavone (2). Compound 1 is a new compound, and compounds 1 and 2 showed weak activity against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus.
为研究木榄内生真菌青霉属FJ-1的化学成分，采用硅胶柱色谱和葡聚糖凝胶LH-20柱色谱对其化学成分进行分离。通过光谱分析对其结构进行鉴定。采用纸片扩散法测试其抗菌活性。分离鉴定出2个化合物，分别为7-羟基脱氧塔拉黄酮（1）和脱氧塔拉黄酮（2）。化合物1为新化合物，化合物1和2对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌均显示出较弱的活性。
