Council for Agricultural Research and Agricultural Economy Analysis, 00184 Rome, Italy.
Department of Agriculture, University of Naples 'Federico II', 80055 Portici, Italy.
Mar Drugs. 2018 Jan 6;16(1):12. doi: 10.3390/md16010012.
Boosted by the general aim of exploiting the biotechnological potential of the microbial component of biodiversity, research on the secondary metabolite production of endophytic fungi has remarkably increased in the past few decades. Novel compounds and bioactivities have resulted from this work, which has stimulated a more thorough consideration of various natural ecosystems as conducive contexts for the discovery of new drugs. Thriving at the frontier between land and sea, mangrove forests represent one of the most valuable areas in this respect. The present paper offers a review of the research on the characterization and biological activities of secondary metabolites from manglicolous strains of species belonging to the genus . Aspects concerning the opportunity for a more reliable identification of this biological material in the light of recent taxonomic revisions are also discussed.
在利用生物多样性中微生物成分的生物技术潜力的总体目标的推动下,过去几十年中,对内生真菌次生代谢产物生产的研究显著增加。这项工作产生了新的化合物和生物活性,这促使人们更深入地考虑各种自然生态系统作为发现新药的有利环境。在陆地和海洋的前沿蓬勃发展的红树林代表了这方面最有价值的区域之一。本文综述了对属于属的红树林菌株的次生代谢产物的特征和生物活性的研究。还讨论了根据最近的分类修订更可靠地鉴定这种生物材料的机会。