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毛霉菌病——从病原体到疾病。

Mucormycosis--from the pathogens to the disease.

机构信息

Division of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria.

出版信息

Clin Microbiol Infect. 2014 Jun;20 Suppl 6:60-6. doi: 10.1111/1469-0691.12566. Epub 2014 Feb 24.

DOI:10.1111/1469-0691.12566
PMID:24476149
Abstract

Mucormycosis is an emerging fungal infection worldwide, with devastating disease symptoms and diverse clinical manifestations. The most important underlying risk factors are immunosuppression, poorly controlled diabetes, iron overload and major trauma. The aetiological agents involved in the disease have been re-classified due to changes in taxonomy and nomenclature, which also led to appropriately naming the disease 'mucormycosis'. This article shortly explains the new nomenclature, clinical manifestations and risk factors and focuses on putative virulence traits associated with mucormycosis, mainly in the group of diabetic ketoacidotic patients.

摘要

毛霉病是一种在全球范围内不断出现的真菌感染,具有破坏性的疾病症状和多种临床表现。最重要的潜在风险因素包括免疫抑制、未得到良好控制的糖尿病、铁过载和重大创伤。由于分类学和命名法的改变,参与该疾病的病原体已被重新分类,这也导致该疾病被恰当地命名为“毛霉病”。本文简要介绍了新的命名法、临床表现和风险因素,并重点介绍了与毛霉病相关的潜在毒力特征,主要是在糖尿病酮症酸中毒患者群体中。

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Mucormycosis--from the pathogens to the disease.毛霉菌病——从病原体到疾病。
Clin Microbiol Infect. 2014 Jun;20 Suppl 6:60-6. doi: 10.1111/1469-0691.12566. Epub 2014 Feb 24.
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Ketoacidosis alone does not predispose to mucormycosis by Lichtheimia in a murine pulmonary infection model.酮症酸中毒本身并不会使小鼠肺部感染模型中的 Lichtheimia 毛霉菌易感性增加。
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Epidemiology and treatment of mucormycosis.毛霉菌病的流行病学和治疗。
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Taxonomy of fungi causing mucormycosis and entomophthoramycosis (zygomycosis) and nomenclature of the disease: molecular mycologic perspectives.真菌引起的毛霉病和虫霉病(接合菌病)的分类学和疾病的命名:分子真菌学观点。
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[Laboratory diagnosis of mucormycosis].[毛霉病的实验室诊断]
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Mucormycoses caused by Lichtheimia species.由犁头霉属物种引起的毛霉病。
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