Yadav Riya, Parihar Pratapsingh, Yadav Suyash, Yadav Shweta
Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Acharya Vinoba Bhave Rural Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Department of Pathology, Shri Shankaracharya Institute of Medical Sciences, Durg, IND.
Cureus. 2024 Sep 7;16(9):e68873. doi: 10.7759/cureus.68873. eCollection 2024 Sep.
The maxilla is a facial bone with a dense blood supply. Although rare, infections, trauma, and certain metabolic disorders can lead to necrosis of the maxillary bone. The maxilla, a vital bone forming the roof of the oral cavity, is particularly susceptible to mucormycosis, a prevalent fungal infection, especially in individuals with diabetes and compromised immune systems. Here, we discuss mucormycosis-associated maxillary necrosis in a patient with uncontrolled diabetes. Early identification and treatment of this lethal fungal infection can significantly reduce its mortality and morbidity rates. Due to the maxilla's high vascularity, necrosis is uncommon. However, various infections, including bacterial, viral, and fungal, can lead to maxillary necrosis. Other potential causes include trauma, radiation, prolonged corticosteroid use, and lipid metabolism disorders (like Gaucher disease). Early diagnosis and timely treatment are crucial to significantly reducing the mortality and morbidity associated with this life-threatening fungal infection.
上颌骨是一块血供丰富的面骨。虽然罕见，但感染、创伤和某些代谢紊乱可导致上颌骨坏死。上颌骨是构成口腔顶部的重要骨骼，特别容易发生毛霉菌病，这是一种常见的真菌感染，尤其是在糖尿病患者和免疫系统受损的个体中。在此，我们讨论一名糖尿病控制不佳患者的毛霉菌病相关上颌骨坏死。早期识别和治疗这种致命的真菌感染可显著降低其死亡率和发病率。由于上颌骨血管丰富，坏死并不常见。然而，包括细菌、病毒和真菌在内的各种感染都可导致上颌骨坏死。其他潜在原因包括创伤、放疗、长期使用皮质类固醇以及脂质代谢紊乱（如戈谢病）。早期诊断和及时治疗对于显著降低与这种危及生命的真菌感染相关的死亡率和发病率至关重要。
