Schofield Peter William, Moore Tammie Maree, Gardner Andrew
Neuropsychiatry Service, Hunter New England Mental Health , Newcastle, NSW , Australia ; Centre for Translational Neuroscience and Mental Health, University of Newcastle , Newcastle, NSW , Australia.
Neuropsychiatry Service, Hunter New England Mental Health , Newcastle, NSW , Australia.
Front Neurol. 2014 Jan 22;5:5. doi: 10.3389/fneur.2014.00005. eCollection 2014.
Traumatic brain injury (TBI) is a common condition that is often complicated by neuropsychiatric sequelae that can have major impacts on function and quality of life. An alteration in the sense of smell is recognized as a relatively common complication of TBI; however in clinical practice, this complication may not be sought or adequately characterized. We conducted a systematic review of studies concerned with olfactory functioning following TBI. Our predetermined criteria led to the identification of 25 studies published in English, which we examined in detail. We have tabulated the data from these studies in eight separate tables, beginning with Table 1, which highlights each study's key findings, and we provide a summary/synthesis of the findings in the accompanying results and discussion sections. Despite widely differing methodologies, the studies attest to a high frequency of post-TBI olfactory dysfunction and indicate that its presence can serve as a potential marker of additional structural or functional morbidities.
创伤性脑损伤（TBI）是一种常见病症，常伴有神经精神后遗症，这些后遗症会对功能和生活质量产生重大影响。嗅觉改变被认为是TBI相对常见的并发症；然而在临床实践中，可能不会对这种并发症进行排查或充分描述。我们对有关TBI后嗅觉功能的研究进行了系统综述。我们预先设定的标准使我们确定了25项以英文发表的研究，并对其进行了详细审查。我们已将这些研究的数据整理在八个单独的表格中，从表1开始，该表突出了每项研究的主要发现，并且我们在随附的结果和讨论部分提供了研究结果的总结/综合分析。尽管研究方法差异很大，但这些研究证明TBI后嗅觉功能障碍的发生率很高，并表明其存在可作为额外结构或功能病变的潜在标志物。
