Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Decatur, GA, United States; Emory University, Rollins School of Public Health, Department of Behavioral Sciences and Health Education, Atlanta, GA, United States.
Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Decatur, GA, United States; Emory University, Rollins School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States.
Vaccine. 2014 Mar 26;32(15):1736-44. doi: 10.1016/j.vaccine.2014.01.030. Epub 2014 Jan 28.
A suboptimal level of seasonal influenza vaccination among pregnant minority women is an intractable public health problem, requiring effective message resonance with this population. We evaluated the effects of randomized exposure to messages which emphasize positive outcomes of vaccination ("gain-frame"), or messages which emphasize negative outcomes of forgoing vaccination ("loss-frame"). We also assessed multilevel social and community factors that influence maternal immunization among racially and ethnically diverse populations.
Minority pregnant women in metropolitan Atlanta were enrolled in the longitudinal study and randomized to receive intervention or control messages. A postpartum questionnaire administered 30 days postpartum evaluated immunization outcomes following baseline message exposure among the study population. We evaluated key outcomes using bivariate and multivariate analyses.
Neither gain- [OR=0.5176, (95% CI: 0.203,1.322)] nor loss-framed [OR=0.5000, 95% CI: (0.192,1.304)] messages were significantly associated with increased likelihood of immunization during pregnancy. Significant correlates of seasonal influenza immunization during pregnancy included healthcare provider recommendation [OR=3.934, 95% CI: (1.331,11.627)], use of hospital-based practices as primary source of prenatal care [OR=2.584, 95% CI: (1.091,6.122)], and perceived interpersonal support for influenza immunization [OR=3.405, 95% CI: (1.412,8.212)].
Dissemination of vaccine education messages via healthcare providers, and cultivating support from social networks, will improve seasonal influenza immunization among pregnant minority women.
少数族裔孕妇季节性流感疫苗接种率不理想,是一个棘手的公共卫生问题,需要针对这一人群有效传递信息。我们评估了随机接触强调接种疫苗积极结果(“增益框架”)或强调放弃接种疫苗负面结果(“损失框架”)信息的效果。我们还评估了影响不同种族和族裔孕妇群体中母婴免疫的多层次社会和社区因素。
亚特兰大都会区的少数族裔孕妇参与了这项纵向研究,并被随机分配接受干预或对照信息。产后 30 天进行的问卷调查评估了研究人群在基线信息暴露后疫苗接种的结果。我们使用双变量和多变量分析评估了关键结果。
增益框架[OR=0.5176,(95%CI:0.203,1.322)]和损失框架[OR=0.5000,(95%CI:0.192,1.304)]信息均与怀孕期间增加疫苗接种的可能性无显著相关性。怀孕期间季节性流感免疫的显著相关因素包括医疗保健提供者的建议[OR=3.934,95%CI:(1.331,11.627)]、使用以医院为基础的实践作为主要产前保健来源[OR=2.584,95%CI:(1.091,6.122)]以及对流感免疫的人际支持感知[OR=3.405,95%CI:(1.412,8.212)]。
通过医疗保健提供者传播疫苗教育信息,并培养社交网络的支持,将提高少数族裔孕妇季节性流感免疫接种率。