鼻部肿瘤——转移性肺癌的一种罕见表现
Tumor of the Nose - A Rare Manifestation of a Metastatic Lung Cancer.
作者信息
Bolewska Aleksandra, Słowińska Monika, Błońska Agata, Ceryn Justyna, Grala Bartłomiej, Narbutt Joanna, Ciążyńska Magdalena, Małecki Wojciech, Skibińska Małgorzata, Lesiak Aleksandra, Paluchowska Elwira, Owczarek Witold
机构信息
Department of Dermatology, Military Institute of Medicine, Warsaw, Poland.
Department of Dermatology, Pediatric Dermatology and Oncology, Medical University of Lodz, Łódź, Poland.
出版信息
Clin Cosmet Investig Dermatol. 2021 Sep 21;14:1311-1318. doi: 10.2147/CCID.S318748. eCollection 2021.
Lung cancer most often metastasizes to the central nervous system, bone and liver. Although metastases to the skin are quite rare, it is estimated that they may be the first clinical manifestation of this disease in 0.7%-12% of cases. Metastases to the skin are caused by adenocarcinoma (about 30%), squamous cell carcinoma (30%) and undifferentiated carcinoma (40%). Nasal tip metastases are extremely rare. They can be confused with more common skin problems, including non-melanoma skin cancers, rhinophyma, inflammatory tumors or infectious diseases. We report two patients with a tumor on the nose, which proved to be the first sign of the metastatic lung cancer.
肺癌最常转移至中枢神经系统、骨骼和肝脏。虽然皮肤转移相当罕见，但据估计在0.7%-12%的病例中，皮肤转移可能是该疾病的首发临床表现。皮肤转移由腺癌（约30%）、鳞状细胞癌（30%）和未分化癌（40%）引起。鼻尖转移极为罕见。它们可能与更常见的皮肤问题相混淆，包括非黑素瘤皮肤癌、酒渣鼻、炎性肿瘤或传染病。我们报告了两名鼻部有肿瘤的患者，结果证明这是转移性肺癌的首个体征。
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