Norlén H, Allgén L G, Vinnars E, Wiklund A
Department of Urology, St Erik's Hospital, Stockholm, Sweden.
Scand J Urol Nephrol. 1987;21(3):161-8. doi: 10.3109/00365598709180317.
Eight patients undergoing transurethral resection of the prostate (TURP) using sterile distilled water as an irrigating fluid were studied. The concentrations of plasma haemoglobin, serum sodium, serum prostatic acid phosphatase protein (PAP) and plasma osmolality were determined as possible indicators of absorption of irrigating fluid. In 3 patients there was a marked increase in plasma haemoglobin immediately postoperatively with a maximum of 3.3 g haemoglobin/l plasma. In the remaining 5 patients the plasma haemoglobin level did not exceed 0.7 g/l immediately postoperatively. In all cases there was a fairly rapid return of the elevated plasma haemoglobin level to preoperative values. There was also a postoperative increase in the serum PAP level which was not correlated with the simultaneous increase in plasma haemoglobin concentration. There was no significant change in the sodium, potassium or albumin concentration in serum nor in plasma osmolality postoperatively. There was some decrease in the postoperative serum creatinine and uric acid levels. The preoperative serum creatinine concentration was within reference limits in 7 patients and borderline high in 1 patient. The haemoglobin binding plasma protein haptoglobin showed a slight non-significant increase immediately postoperatively and a significant decrease in concentration 2 hours postoperatively. The mean plasma haemoglobin concentration immediately postoperatively did not exceed the mean preoperative haemoglobin binding capacity of serum. The mean preoperative haemoglobin binding capacity was 1.2 g/l and the mean plasma haemoglobin level was 1.2 g/l immediately postoperatively. Two hours later the mean plasma haemoglobin level was 0.8 g/l. The mean serum haptoglobin concentration was 2.4 g/l preoperatively, 2.6 g/l immediately postoperatively and 2.0 g/l 2 hours later.(ABSTRACT TRUNCATED AT 250 WORDS)
对8例使用无菌蒸馏水作为冲洗液进行经尿道前列腺切除术（TURP）的患者进行了研究。测定血浆血红蛋白、血清钠、血清前列腺酸性磷酸酶蛋白（PAP）浓度和血浆渗透压，作为冲洗液吸收的可能指标。3例患者术后即刻血浆血红蛋白显著升高，最高达3.3g血红蛋白/升血浆。其余5例患者术后即刻血浆血红蛋白水平不超过0.7g/升。所有病例中，升高的血浆血红蛋白水平均较快恢复至术前值。术后血清PAP水平也有升高，与血浆血红蛋白浓度同时升高无关。术后血清钠、钾或白蛋白浓度以及血浆渗透压均无显著变化。术后血清肌酐和尿酸水平有所下降。7例患者术前血清肌酐浓度在参考范围内，1例患者临界偏高。血红蛋白结合血浆蛋白触珠蛋白术后即刻略有升高但无统计学意义，术后2小时浓度显著下降。术后即刻血浆血红蛋白平均浓度未超过术前血清血红蛋白结合能力均值。术前血红蛋白结合能力均值为1.2g/升，术后即刻血浆血红蛋白水平为1.2g/升。2小时后血浆血红蛋白平均水平为0.8g/升。术前血清触珠蛋白平均浓度为2.4g/升，术后即刻为2.6g/升，2小时后为2.0g/升。（摘要截短至250字）
