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千里光（菊科）：一种有前途的抗氧化剂来源。

Vernonia condensata Baker (Asteraceae): a promising source of antioxidants.

机构信息

Graduate Program in Pharmaceutical Sciences, Federal University of Juiz de Fora, Campus Universitário, 36036-330 Juiz de Fora, MG, Brazil ; Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, 36036-330 Juiz de Fora, MG, Brazil.

Faculty of Pharmacy, Federal University of Juiz de Fora, Campus Universitário, 36036-330 Juiz de Fora, MG, Brazil.

出版信息

Oxid Med Cell Longev. 2013;2013:698018. doi: 10.1155/2013/698018. Epub 2013 Dec 31.

DOI:10.1155/2013/698018
PMID:24489987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3893806/
Abstract

The present study evaluated the antioxidant potential of Vernonia condensata Baker (Asteraceae). Dried and powdered leaves were exhaustively extracted with ethanol by static maceration followed by partition to obtain the hexane, dichloromethane, ethyl acetate, and butanol fractions. Total phenols and flavonoids contents were determined through spectrophotometry and flavonoids were identified by HPLC-DAD system. The antioxidant activity was assessed by DPPH radical scavenging activity, TLC-bioautography, reducing power of Fe(+3), phosphomolybdenum, and TBA assays. The total phenolic content and total flavonoids ranged from 0.19 to 23.11 g/100 g and from 0.13 to 4.10 g/100 g, respectively. The flavonoids apigenin and luteolin were identified in the ethyl acetate fraction. The IC50 of DPPH assay varied from 4.28 to 75.10 µg/mL and TLC-bioautography detected the antioxidant compounds. The reducing power of Fe(+3) was 19.98 to 336.48  μg/mL, while the reaction with phosphomolybdenum ranged from 13.54% to 32.63% and 56.02% to 135.00% considering ascorbic acid and rutin as reference, respectively. At 30 mg/mL, the ethanolic extract and fractions revealed significant effect against lipid peroxidation. All these data sustain that V. condensata is an important and promising source of bioactive substances with antioxidant activity.

摘要

本研究评估了 Vernonia condensata Baker（菊科）的抗氧化潜力。将干燥和粉碎的叶子用乙醇进行静态浸提，然后进行分配，以获得正己烷、二氯甲烷、乙酸乙酯和正丁醇部分。通过分光光度法测定总酚和类黄酮含量，并通过 HPLC-DAD 系统鉴定类黄酮。通过 DPPH 自由基清除活性、TLC-生物自显影、Fe(+3)还原能力、磷钼酸盐和 TBA 测定评估抗氧化活性。总酚含量和总类黄酮含量分别在 0.19 至 23.11 μg/100 g 和 0.13 至 4.10 g/100 g 之间。在乙酸乙酯部分鉴定出类黄酮芹菜素和木樨草素。DPPH 测定的 IC50 范围为 4.28 至 75.10 μg/mL，TLC-生物自显影检测到抗氧化化合物。Fe(+3)的还原能力为 19.98 至 336.48 μg/mL，而与磷钼酸盐的反应分别为 13.54%至 32.63%和 56.02%至 135.00%，以抗坏血酸和芦丁为参考。在 30 mg/mL 时，乙醇提取物和馏分对脂质过氧化有显著作用。所有这些数据表明，V. condensata 是一种具有抗氧化活性的生物活性物质的重要且有前途的来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cc/3893806/3157acf26341/OXIMED2013-698018.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cc/3893806/c1a6a4824c4f/OXIMED2013-698018.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cc/3893806/3157acf26341/OXIMED2013-698018.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cc/3893806/c1a6a4824c4f/OXIMED2013-698018.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cc/3893806/3157acf26341/OXIMED2013-698018.002.jpg

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本文引用的文献

1
Free radicals, antioxidants in disease and health.自由基、疾病与健康中的抗氧化剂
Int J Biomed Sci. 2008 Jun;4(2):89-96.
2
Assessment of flavonoids contents and in vitro antioxidant activity of Launaea procumbens.平卧菜黄酮含量及体外抗氧化活性的测定
Chem Cent J. 2012 May 22;6(1):43. doi: 10.1186/1752-153X-6-43.
3
New approaches to clarify antinociceptive and anti-inflammatory effects of the ethanol extract from Vernonia condensata leaves.阐明聚生斑鸠菊叶乙醇提取物的抗伤害感受和抗炎作用的新方法。
Inhibitory effects of tangeretin and trans-ethyl caffeate on the HMG-CoA reductase activity: Potential agents for reducing cholesterol levels.陈皮素和反式咖啡酸乙酯对HMG-CoA还原酶活性的抑制作用：降低胆固醇水平的潜在药物。
Saudi J Biol Sci. 2020 Aug;27(8):1947-1960. doi: 10.1016/j.sjbs.2020.06.010. Epub 2020 Jun 17.
4
Recent Trends in the Application of Chromatographic Techniques in the Analysis of Luteolin and Its Derivatives.近年来色谱技术在芦丁及其衍生物分析中的应用进展。
Biomolecules. 2019 Nov 12;9(11):731. doi: 10.3390/biom9110731.
5
Eco-friendly synthesis, characterization, in vitro and in vivo anti-inflammatory activity of silver nanoparticle-mediated aqueous extract.环保型合成、银纳米粒子介导的水提物的表征、体外和体内抗炎活性。
Int J Nanomedicine. 2018 Dec 12;13:8537-8548. doi: 10.2147/IJN.S174530. eCollection 2018.
6
Antioxidant Treatment Induces Hyperactivation of the HPA Axis by Upregulating ACTH Receptor in the Adrenal and Downregulating Glucocorticoid Receptors in the Pituitary.抗氧化剂治疗通过上调肾上腺中的促肾上腺皮质激素（ACTH）受体和下调垂体中的糖皮质激素受体来诱导下丘脑-垂体-肾上腺（HPA）轴的过度激活。
Oxid Med Cell Longev. 2017;2017:4156361. doi: 10.1155/2017/4156361. Epub 2017 May 9.
7
Vernonia kotschyana roots: therapeutic potential via antioxidant activity.科氏斑鸠菊根：通过抗氧化活性发挥的治疗潜力。
Molecules. 2014 Nov 19;19(11):19114-36. doi: 10.3390/molecules191119114.
Int J Mol Sci. 2011;12(12):8993-9008. doi: 10.3390/ijms12128993. Epub 2011 Dec 7.
4
Antioxidant activity of food constituents: an overview.食物成分的抗氧化活性：概述。
Arch Toxicol. 2012 Mar;86(3):345-91. doi: 10.1007/s00204-011-0774-2. Epub 2011 Nov 20.
5
Evaluation of antioxidant potential of flavonoids: an in vitro study.黄酮类化合物抗氧化潜力的评估：一项体外研究。
Acta Pol Pharm. 2011 Jul-Aug;68(4):611-5.
6
Antinociceptive and acute toxicity evaluation of Vernonia condensata Baker leaves extracted with different solvents and their mixtures.用不同溶剂及其混合物提取的凝叶斑鸠菊叶的抗伤害感受和急性毒性评估。
Indian J Exp Biol. 2010 Aug;48(8):811-6.
7
Free radical scavenging activity and characterization of sesquiterpenoids in four species of Curcuma using a TLC bioautography assay and GC-MS analysis.四种莪术属植物倍半萜的自由基清除活性及化学成分的 TLC 生物自显影分析和 GC-MS 分析。
Molecules. 2010 Oct 27;15(11):7547-57. doi: 10.3390/molecules15117547.
8
New flavonoid glycosides from Vernonia ferruginea.来自铁锈叶斑鸠菊的新黄酮苷。
Nat Prod Commun. 2009 Dec;4(12):1639-42.
9
Free radicals and antioxidants in normal physiological functions and human disease.正常生理功能和人类疾病中的自由基与抗氧化剂
Int J Biochem Cell Biol. 2007;39(1):44-84. doi: 10.1016/j.biocel.2006.07.001. Epub 2006 Aug 4.
10
Anti-inflammatory and antinociceptive activity of flavonoids isolated from Viscum album ssp. album.从欧洲槲寄生中分离出的黄酮类化合物的抗炎和镇痛活性。
Z Naturforsch C J Biosci. 2006 Jan-Feb;61(1-2):26-30. doi: 10.1515/znc-2006-1-205.