遗传性血栓形成倾向与不良妊娠结局：筛查模式及建议综述
Inherited thrombophilias and adverse pregnancy outcomes: a review of screening patterns and recommendations.
作者信息
Davenport William B, Kutteh William H
机构信息
Department of Obstetrics and Gynecology, University of Vermont, 89 Beaumont Avenue, Given C262, Burlington, VT 05406, USA.
Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Fertility Associates of Memphis, 80 Humphreys Center, Suite 307, Memphis, TN 38120, USA.
出版信息
Obstet Gynecol Clin North Am. 2014 Mar;41(1):133-44. doi: 10.1016/j.ogc.2013.10.005. Epub 2013 Dec 10.
Historically, much controversy has existed regarding the association of inherited thrombophilias with adverse pregnancy outcomes. The current guidelines do not recommend screening unless a personal history of venous thromboembolism is present, but the authors' survey of physician screening patterns has suggested that up to 40% of physicians may screen contrary to the current guidelines. This article summarizes the existing evidence for each inherited thrombophilia and reviews the current guidelines.
从历史上看，关于遗传性血栓形成倾向与不良妊娠结局之间的关联一直存在很多争议。目前的指南不建议进行筛查，除非有静脉血栓栓塞的个人病史，但作者对医生筛查模式的调查表明，高达40%的医生可能会违反当前指南进行筛查。本文总结了每种遗传性血栓形成倾向的现有证据，并回顾了当前的指南。
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