Palacios Isabel M
Zoology Department, University of Cambridge, Cambridge CB2 3EJ, England, UK.
J Cell Biol. 2014 Feb 3;204(3):287-9. doi: 10.1083/jcb.201401019.
After export from the nucleus, ribosomes need to be distributed throughout the entire cell so that protein synthesis can occur even at distant sites. In the elongated hyphal cell of the fungus Ustilago maydis, Higuchi et al. (2014. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201307164) now demonstrate that polysomes associate with early endosomes that undergo kinesin 3- and dynein-dependent long-range motility. The bidirectional movement of early endosomes randomly distributes polysomes, which may ensure the even distribution of the translation machinery across the entire cell.
从细胞核输出后，核糖体需要分布于整个细胞，以便即使在较远的位点也能进行蛋白质合成。在真菌玉米黑粉菌的细长菌丝细胞中，Higuchi等人（2014年，《细胞生物学杂志》，http://dx.doi.org/10.1083/jcb.201307164）现在证明，多核糖体与早期内体相关联，早期内体经历驱动蛋白3和动力蛋白依赖的长距离运动。早期内体的双向运动随机分布多核糖体，这可能确保翻译机器在整个细胞中的均匀分布。
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