腹膜后Castleman病：倡导针对这一罕见临床实体的多学科方法。
Retroperitoneal Castleman's disease: advocating a multidisciplinary approach for a rare clinical entity.
作者信息
Williams Austin D, Sanchez Adriana, Hou Jun Steve, Rubin Rene Rothstein, Hysell Mark E, Babcock Blake D, Shaikh Mohammad F, Weingarten Michael S, Bowne Wilbur B
机构信息
Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N, 15th St,, MS 413, Philadelphia, PA 19102, USA.
出版信息
World J Surg Oncol. 2014 Feb 4;12:30. doi: 10.1186/1477-7819-12-30.
BACKGROUND
Castleman's disease is a rare and poorly understood disease entity that may resemble more common conditions and represents a clinical challenge to the treating surgeon.
CASE PRESENTATION
In this report, we describe a case of a 61-year-old Caucasian woman with a symptomatic retroperitoneal mass. The specimen obtained from her resection contained a protuberant encapsulated mass, exhibiting microscopic features consistent with localized, unicentric Castleman's disease. These characteristics included architectural features and immunohistochemical findings consistent with the hyaline vascular variant of Castleman's disease.
CONCLUSION
We report a very rare case of a retroperitoneal hyaline vascular type of Castleman's disease. We discuss the diagnostic dilemma Castleman's disease may present to the surgeon, with an emphasis on multidisciplinary management of these patients. We also review current data on pathogenesis, treatment and outcomes.
背景
卡斯特曼病是一种罕见且了解甚少的疾病实体，可能类似于更常见的病症，给主治外科医生带来临床挑战。
病例介绍
在本报告中，我们描述了一名61岁有症状的腹膜后肿块白种女性病例。从她的切除标本中发现一个突出的包膜肿块，显微镜下特征符合局限性单中心卡斯特曼病。这些特征包括与卡斯特曼病透明血管型一致的结构特征和免疫组化结果。
结论
我们报告了一例非常罕见的腹膜后透明血管型卡斯特曼病病例。我们讨论了卡斯特曼病可能给外科医生带来的诊断困境，重点是这些患者的多学科管理。我们还回顾了目前关于发病机制、治疗和结果的数据。
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