受生物启发的锰配合物催化的高效苄基和脂肪族 C-H 氧化反应，具有对亚甲基位点的选择性。
Efficient benzylic and aliphatic C-H oxidation with selectivity for methylenic sites catalyzed by a bioinspired manganese complex.
机构信息
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics , Chinese Academy of Sciences, Lanzhou, 730000, PR China.
出版信息
Org Lett. 2014 Feb 21;16(4):1108-11. doi: 10.1021/ol4037083. Epub 2014 Feb 6.
PMID:24499500
Abstract
A benzimidazole-based nonheme manganese complex efficiently catalyzes benzylic, aliphatic C-H as well as tertiary C-H oxidation with hydrogen peroxide as the oxidant in the presence of acetic acid as additive. (18)O labeling experiments suggest the reaction may proceed via a high-valent manganese-oxo intermediate.
摘要
一种基于苯并咪唑的非血红素锰配合物在醋酸作为添加剂的存在下，能够有效地催化苄基、脂肪族 C-H 和叔 C-H 的氧化，使用过氧化氢作为氧化剂。（18）O 标记实验表明，该反应可能通过高价锰-氧中间体进行。
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