Department of General Microbiology, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Biotechnol Biofuels. 2013 Oct 21;6(1):152. doi: 10.1186/1754-6834-6-152.
One of the main obstacles for continuous productivity in microalgae cultivation is the presence of biological contaminants capable of eliminating large numbers of cells in a matter of days or even hours. However, a number of strategies are being used to combat and prevent contamination in microalgae cultivation. These strategies include the use of extreme conditions in the culture media such as high salinity and high pH to create an unfavorable environment for the competitive organisms or predators of the microalgae. Numerous studies have explored the potential of naturally occurring bioactive secondary metabolites, which are natural products from plants and microorganisms, as a source of such compounds. Some of these compounds are herbicides, and marine and freshwater microalgae are a source of these compounds. Microalgae produce a remarkable diversity of biologically active metabolites. Results based on the allelopathic potential of algae have only been described for laboratory-scale production and not for algae cultivation on a pilot scale. The adoption of allelopathy on microalgal strains is an unexplored field and may be a novel solution to improve algae production. Here we present information showing the diversity of allelochemicals from microalgae and the use of an allelopathic approach to control microalgae cultivation on a pilot scale based on R&D activities being carried out in Brazil for biodiesel production.
在微藻培养中，持续生产力的主要障碍之一是存在能够在数天甚至数小时内消灭大量细胞的生物污染物。然而，许多策略正在被用于对抗和防止微藻培养中的污染。这些策略包括在培养介质中使用极端条件，如高盐度和高 pH 值，为微藻的竞争生物或捕食者创造不利的环境。许多研究都探讨了天然存在的生物活性次生代谢物的潜力，这些化合物是植物和微生物的天然产物，是此类化合物的来源。其中一些化合物是除草剂，而海洋和淡水微藻是这些化合物的来源。微藻产生了多种多样具有生物活性的代谢物。基于藻类化感潜力的结果仅在实验室规模生产中进行了描述，而不在藻类培养的中试规模上进行描述。化感作用对微藻菌株的采用是一个尚未开发的领域，可能是提高藻类生产的一种新方法。在这里，我们提供了微藻化感化合物多样性的信息，并展示了基于巴西正在进行的生物柴油生产的研发活动，在中试规模上利用化感方法来控制微藻培养的信息。
