Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, Brigadeiro Trompowski avenue, CCS building, - J block J - second floor - District: Ilha do Fundão, 360 Felisbelo Freire Street, Apartament 202 District: Ramos, Zipe Code: 21941-590, Rio de Janeiro, Brazil.
Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Diabetol Metab Syndr. 2013 Nov 12;5(1):67. doi: 10.1186/1758-5996-5-67.
It is unclear if the sugar intake may affect metabolic parameters in individuals with type 1 diabetes. Therefore, the purpose of this study was to evaluate the effects of sucrose intake in glycemic, lipemic, anthropometric variables, as well as in C-reactive protein (CRP) levels in these individuals.
Thirty-three subjects with type 1 diabetes were evaluated at baseline and 3-months after intervention. Volunteers were randomized into groups: sucrose-free (diet without sucrose) or sucrose-added (foods containing sucrose in composition). Both groups received the same macronutrient composition and used the carbohydrate counting methods. All underwent an interview and anthropometric evaluation. Blood was drawn for glycated haemoglobin, glucose, total cholesterol, HDL, and CRP measurement, and the medical charts were reviewed in all cases.
At baseline, anthropometric, clinical and laboratory variables did not differ between groups, except for the triglycerides. Although at baseline triglycerides levels were higher in the sucrose-added group (p = 0.01), they did not differ between groups after the intervention (p = 0.92). After 3-months, CRP was higher in the sucrose-added than in the sucrose-free group (p = 0.04), but no further differences were found between the groups, including the insulin requirements, anthropometric variables, body composition, and glycemic control. Both groups showed sugars intake above the recommendations at baseline and after intervention.
Sucrose intake, along with a disciplined diet, did not affect insulin requirements, anthropometric variables, body composition, lipemic and glycemic control. However, although the sucrose intakes increase CRP levels, the amount of sugar in the diet was not associated with this inflammatory marker.
目前尚不清楚糖的摄入量是否会影响 1 型糖尿病患者的代谢参数。因此，本研究的目的是评估蔗糖摄入对这些个体的血糖、血脂、人体测量学变量以及 C 反应蛋白（CRP）水平的影响。
33 名 1 型糖尿病患者在基线和干预后 3 个月进行评估。志愿者随机分为两组：无蔗糖（不含蔗糖的饮食）或添加蔗糖（组成中含有蔗糖的食物）。两组均接受相同的宏量营养素组成，并使用碳水化合物计数法。所有患者均接受访谈和人体测量评估。抽取血液用于糖化血红蛋白、葡萄糖、总胆固醇、HDL 和 CRP 测量，并对所有患者的病历进行回顾。
基线时，两组的人体测量、临床和实验室变量均无差异，除了甘油三酯。尽管添加蔗糖组的甘油三酯水平较高（p=0.01），但干预后两组间无差异（p=0.92）。3 个月后，添加蔗糖组的 CRP 高于无蔗糖组（p=0.04），但两组间无进一步差异，包括胰岛素需求、人体测量学变量、身体成分和血糖控制。两组在基线和干预后均显示出高于推荐量的糖摄入量。
蔗糖摄入与规律饮食一起，不会影响胰岛素需求、人体测量学变量、身体成分、血脂和血糖控制。然而，尽管蔗糖摄入增加了 CRP 水平，但饮食中的糖量与这种炎症标志物无关。
