Ruedy J
Department of Medicine, St Paul's Hospital, University of British Columbia, Vancouver.
Clin Invest Med. 1987 Nov;10(6):592-6.
Abnormalities in cellular sodium transport have been demonstrated in leukocytes and erythrocytes of some patients with essential hypertension. Some patients with essential hypertension retain more sodium on a high-salt diet, despite an accompanying increase in pressure. Some epidemiological studies suggest a relationship between dietary sodium intake and essential hypertension. The biological significance of these findings remains uncertain. There is too little evidence to support dietary sodium restriction as a primary preventive measure in essential hypertension. Restriction of dietary intake of sodium to 80 mmol/day results in a reduction in blood pressure in a minority of patients with essential hypertension.
在一些原发性高血压患者的白细胞和红细胞中，已证实存在细胞钠转运异常。一些原发性高血压患者在高盐饮食时会潴留更多的钠，尽管血压随之升高。一些流行病学研究表明饮食钠摄入量与原发性高血压之间存在关联。这些发现的生物学意义仍不确定。几乎没有证据支持将限制饮食钠摄入作为原发性高血压的主要预防措施。将饮食钠摄入量限制在每天80毫摩尔可使少数原发性高血压患者的血压降低。
