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碳酸羟基磷灰石功能化：（生物）分子固定的对比研究。

Carbonate hydroxyapatite functionalization: a comparative study towards (bio)molecules fixation.

机构信息

Department of Biotechnology and Biosciences , University of Milano-Bicocca , Piazza della Scienza 2, Milano 20126 , Italy.

Servicio Interdepartamental de Investigación , University Autonoma of Madrid , Madrid 28049 , Spain.

出版信息

Interface Focus. 2014 Feb 6;4(1):20130040. doi: 10.1098/rsfs.2013.0040.

DOI:10.1098/rsfs.2013.0040
PMID:24501671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3886308/
Abstract

Different methods for the functionalization of carbonate hydroxyapatite granules with free amine groups by reaction with (3-aminopropyl)triethoxysilane (APTES) have been compared in order to improve the potential for tethering of bioactive molecules to bioceramics. The combined use of tetraethoxyorthosilicate and APTES with acid catalysis resulted in an evident increase in amine surface grafting.

摘要

不同的方法，用于通过与（3-氨丙基）三乙氧基硅烷（APTES）反应使碳酸羟基磷灰石颗粒官能化，以游离胺基团，以提高生物活性分子与生物陶瓷的连接潜力。四乙氧基正硅酸酯和 APTES 与酸催化的联合使用导致胺表面接枝的明显增加。

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本文引用的文献

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2
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Interface Focus. 2012 Jun 6;2(3):259-77. doi: 10.1098/rsfs.2012.0012. Epub 2012 Mar 22.
3
Epoxide opening versus silica condensation during sol-gel hybrid biomaterial synthesis.在溶胶-凝胶杂化生物材料合成过程中，环氧化物开环与硅烷缩合的比较。
Chemistry. 2013 Jun 10;19(24):7856-64. doi: 10.1002/chem.201204326. Epub 2013 Apr 10.
4
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J Colloid Interface Sci. 2013 Mar 15;394:132-40. doi: 10.1016/j.jcis.2012.11.068. Epub 2013 Jan 5.
5
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6
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Acta Biomater. 2013 Jan;9(1):4457-86. doi: 10.1016/j.actbio.2012.08.023. Epub 2012 Aug 21.
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8
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Philos Trans A Math Phys Eng Sci. 2012 Mar 28;370(1963):1400-21. doi: 10.1098/rsta.2011.0258.
9
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Small. 2012 Feb 20;8(4):592-601, 619. doi: 10.1002/smll.201101941. Epub 2012 Jan 19.
10
Sugar-decorated hydroxyapatite: an inorganic material bioactivated with carbohydrates.糖基化羟基磷灰石：一种经碳水化合物生物活化的无机材料。
Carbohydr Res. 2011 Sep 6;346(12):1564-8. doi: 10.1016/j.carres.2011.04.044. Epub 2011 May 3.