多发性硬化症：磁共振成像与脑脊液检查结果的相关性
Multiple sclerosis: correlation of magnetic resonance imaging with cerebrospinal fluid findings.
作者信息
Honig L S, Siddharthan R, Sheremata W A, Sheldon J J, Sazant A
机构信息
Department of Neurology, University of Miami School of Medicine, FL.
出版信息
J Neurol Neurosurg Psychiatry. 1988 Feb;51(2):277-80. doi: 10.1136/jnnp.51.2.277.
Abstract
MRI examination of 41 patients with clinical definite multiple sclerosis showed white matter lesions of high proton T2 signal consistent with demyelination in 76% and CSF abnormalities present in 76%. Of patients with CSF abnormalities, 26% had normal MRI scans; conversely 26% of patients with MRI abnormalities had negative CSF studies. Thus a significant number of multiple sclerosis patients had negative results on either MRI or CSF examination, while only 5% had normal results on both tests.
摘要
对41例临床确诊的多发性硬化症患者进行的MRI检查显示，76%的患者存在与脱髓鞘相符的高质子T2信号白质病变，76%的患者存在脑脊液异常。在脑脊液异常的患者中，26%的患者MRI扫描正常；相反，在MRI异常的患者中，26%的患者脑脊液检查结果为阴性。因此，相当数量的多发性硬化症患者在MRI或脑脊液检查中结果为阴性，而只有5%的患者两项检查结果均正常。
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