National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Biol Psychiatry. 2015 Jan 1;77(1):6-14. doi: 10.1016/j.biopsych.2014.01.003. Epub 2014 Jan 15.
After many years of unfilled promise, psychiatric genetics has seen an unprecedented number of successes in recent years. We hypothesize that the field has reached an inflection point through a confluence of four key developments: advances in genomics; the orientation of the scientific community around large collaborative team science projects; the development of sample and data repositories; and a policy framework for sharing and accessing these resources. We discuss these domains and their effect on scientific progress and provide a perspective on why we think this is only the beginning of a new era in scientific discovery.
经过多年的无果承诺，精神病遗传学近年来取得了前所未有的成功。我们假设，该领域通过四个关键发展的融合达到了一个转折点：基因组学的进步；科学共同体围绕大型合作团队科学项目的定位；样本和数据存储库的发展；以及共享和访问这些资源的政策框架。我们讨论了这些领域及其对科学进步的影响，并提供了我们认为这只是科学发现新时代开始的原因。
