Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom.
University Health Network, Toronto, Canada.
Cancer Discov. 2015 Nov;5(11):1133-6. doi: 10.1158/2159-8290.CD-15-0821.
The recent explosion of genetic and clinical data generated from tumor genome analysis presents an unparalleled opportunity to enhance our understanding of cancer, but this opportunity is compromised by the reluctance of many in the scientific community to share datasets and the lack of interoperability between different data platforms. The Global Alliance for Genomics and Health is addressing these barriers and challenges through a cooperative framework that encourages "team science" and responsible data sharing, complemented by the development of a series of application program interfaces that link different data platforms, thus breaking down traditional silos and liberating the data to enable new discoveries and ultimately benefit patients.
肿瘤基因组分析产生的遗传和临床数据的爆炸式增长为我们增强对癌症的认识提供了前所未有的机会,但由于科学界许多人不愿意共享数据集,以及不同数据平台之间缺乏互操作性,这一机会受到了损害。全球基因组与健康联盟正在通过一个合作框架来解决这些障碍和挑战,该框架鼓励“团队科学”和负责任的数据共享,同时开发一系列应用程序接口来连接不同的数据平台,从而打破传统的信息孤岛,释放数据,以促进新的发现,并最终使患者受益。