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有氧运动训练后骨骼肌肥大。

Skeletal muscle hypertrophy after aerobic exercise training.

作者信息

Konopka Adam R, Harber Matthew P

机构信息

1Mayo Clinic College of Medicine, Endocrine Research Unit, Rochester, MN; and 2Taylor University, School of Natural and Applied Sciences, Upland, IN.

出版信息

Exerc Sport Sci Rev. 2014 Apr;42(2):53-61. doi: 10.1249/JES.0000000000000007.

DOI:10.1249/JES.0000000000000007
PMID:24508740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4523889/
Abstract

Current dogma suggests that aerobic exercise training has minimal effects on skeletal muscle size. We and others have demonstrated that aerobic exercise acutely and chronically alters protein metabolism and induces skeletal muscle hypertrophy. These findings promote an antithesis to the status quo by providing novel perspective on skeletal muscle mass regulation and insight into exercise countermeasures for populations prone to muscle loss.

摘要

当前的理论认为,有氧运动训练对骨骼肌大小的影响微乎其微。我们和其他研究人员已经证明,有氧运动能急性和慢性地改变蛋白质代谢,并诱导骨骼肌肥大。这些发现通过提供关于骨骼肌质量调节的新观点以及对易发生肌肉流失人群的运动对策的见解,对现状提出了一种对立观点。

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本文引用的文献

1
Markers of human skeletal muscle mitochondrial biogenesis and quality control: effects of age and aerobic exercise training.人类骨骼肌线粒体生物发生和质量控制的标志物:年龄和有氧运动训练的影响。
J Gerontol A Biol Sci Med Sci. 2014 Apr;69(4):371-8. doi: 10.1093/gerona/glt107. Epub 2013 Jul 20.
2
Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle.运动与营养干预以改善衰老骨骼肌中的蛋白质合成障碍。
Exerc Sport Sci Rev. 2013 Oct;41(4):216-23. doi: 10.1097/JES.0b013e3182a4e699.
3
A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.抗阻训练诱导的 PGC-1α 异构体调节骨骼肌肥大。
Cell. 2012 Dec 7;151(6):1319-31. doi: 10.1016/j.cell.2012.10.050.
4
Long-term aerobic exercise is associated with greater muscle strength throughout the life span.长期有氧运动与整个生命周期的肌肉力量增强有关。
J Gerontol A Biol Sci Med Sci. 2013 Jun;68(6):631-8. doi: 10.1093/gerona/gls237. Epub 2012 Dec 3.
5
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6
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Exerc Sport Sci Rev. 2012 Jul;40(3):159-64. doi: 10.1097/JES.0b013e3182575599.
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Am J Clin Nutr. 2012 Jun;95(6):1403-12. doi: 10.3945/ajcn.111.020800. Epub 2012 May 9.
8
Resistance exercise load does not determine training-mediated hypertrophic gains in young men.抗阻训练负荷并不决定年轻男性的训练介导的肥大增益。
J Appl Physiol (1985). 2012 Jul;113(1):71-7. doi: 10.1152/japplphysiol.00307.2012. Epub 2012 Apr 19.
9
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FASEB J. 2011 Sep;25(9):3240-9. doi: 10.1096/fj.11-186437. Epub 2011 May 25.