Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, No. 301., Middle Yanchang Road, Shanghai 200072, P.R. China.
Curr Stem Cell Res Ther. 2014 May;9(3):215-22. doi: 10.2174/1574888x09666140213160853.
Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a member of the polyhydroxyalkanoate (PHA) family. It is the designation of molecules consisting of random co-polymers of 3-hydroxybutyrate and 3- hydroxyhexanoate. PHBHHx plays a significant role in the field of biomedical materials. It has good physical, chemical and mechanical properties, making it potentially useful for a wide range of biomaterials applications. In addition, it has also shown better biocompatibility with different cell types. This paper will introduce the physical, chemical and biological properties of PHBHHx, including biodegradation, hydrophilicity, surface properties and cytocompatibility. The development of PHBHHx in tissue-engineering applications will be discussed. PHBHHx used to repair bone, cartilage, tendons, nerves and vessels will be the focus of discussion.
聚(3-羟基丁酸-co-3-羟基己酸酯)（PHBHHx）是聚羟基烷酸酯（PHA）家族的一员。它是由 3-羟基丁酸和 3-羟基己酸随机共聚而成的分子的名称。PHBHHx 在生物医学材料领域发挥着重要作用。它具有良好的物理、化学和机械性能，使其在广泛的生物材料应用中具有潜在的用途。此外，它还表现出与不同细胞类型更好的生物相容性。本文将介绍 PHBHHx 的物理、化学和生物学特性，包括生物降解性、亲水性、表面性质和细胞相容性。还将讨论 PHBHHx 在组织工程应用中的发展。用于修复骨骼、软骨、肌腱、神经和血管的 PHBHHx 将是讨论的重点。
