用于组织工程的聚（3-羟基丁酸酯-co-3-羟基己酸酯）基支架
Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)-based scaffolds for tissue engineering.
作者信息
Chang H M, Wang Z H, Luo H N, Xu M, Ren X Y, Zheng G X, Wu B J, Zhang X H, Lu X Y, Chen F, Jing X H, Wang L
机构信息
Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Xi'an Medical University, Xi'an, China.
Department of Otolaryngology-Head and Neck Surgery, The Second Hospital, Xi'an Jiaotong University, Xi'an, China.
出版信息
Braz J Med Biol Res. 2014 Jul;47(7):533-9. doi: 10.1590/1414-431x20143930. Epub 2014 May 30.
Abstract
Development and selection of an ideal scaffold is of importance for tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a biocompatible bioresorbable copolymer that belongs to the polyhydroxyalkanoate family. Because of its good biocompatibility, PHBHHx has been widely used as a cell scaffold for tissue engineering. This review focuses on the utilization of PHBHHx-based scaffolds in tissue engineering. Advances in the preparation, modification, and application of PHBHHx scaffolds are discussed.
摘要
开发和选择理想的支架材料对于组织工程至关重要。聚（3-羟基丁酸酯-co-3-羟基己酸酯）（PHBHHx）是一种生物相容性可生物降解的共聚物，属于聚羟基脂肪酸酯家族。由于其良好的生物相容性，PHBHHx已被广泛用作组织工程的细胞支架。本文综述聚焦于基于PHBHHx的支架材料在组织工程中的应用。讨论了PHBHHx支架材料在制备、改性及应用方面的进展。
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